Research with pregnant women: a call to action

Reproductive Health
Margaret Olivia Little, Marisha N Wickremsinhe

Abstract

Despite a global need for the use of medication during pregnancy, the medical research community lacks robust evidence for safety and efficacy of treatments and preventives often taken by pregnant women. Given the biological differences between pregnant women and the rest of the population, the need to gather data on the ways in which medications behave in the pregnant body is critical to the health of pregnant women and their offspring. Three ethical reasons are central to this need: 1. Pregnant women deserve access to effective treatment, 2. Pregnant women deserve access to safe treatment, and 3. Pregnant women deserve equitable access to trials carrying the prospect of direct benefit. In this paper, we introduce and frame this Supplement Issue, which presents important conference proceedings of the 2016 Global Forum on Bioethics in Research meeting held in Buenos Aires, Argentina, on the 3rd and 4th of November.

References

Apr 26, 2011·American Journal of Obstetrics and Gynecology·Allen A MitchellUNKNOWN National Birth Defects Prevention Study
Aug 9, 2011·Journal of Women's Health·Mary A FoulkesJanine A Clayton
Oct 22, 2015·Obstetrics and Gynecology·UNKNOWN Committee on Ethics

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Citations

Sep 19, 2019·Journal of the International AIDS Society·Lee FairlieMatthew Chersich
Jul 17, 2020·Ethics & Human Research·Anna C MastroianniLeslie Meltzer Henry
Dec 20, 2019·Trials·Rieke van der Graaf, Phaik Yeong Cheah
Mar 11, 2020·Perspectives in Clinical Research·Sonali Rajiv KarekarPadmaja Anil Marathe
Nov 30, 2021·Annals of Internal Medicine·Andrea CiaranelloShahin Lockman
Dec 16, 2021·Journal of the International AIDS Society·Anne Drapkin LyerlyLeslie Wolf

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