Resection and graft repair for localized hypertrophic neuropathy

Neurosurgery
J P GruenDavid G Kline

Abstract

Formulation of surgical management recommendations for localized hypertrophic mononeuropathy has been difficult because of the infrequency of the lesion, lack of precise pathological diagnosis, and uncertainties regarding its cause. The purpose of this retrospective review of the Louisiana State University (LSU) experience with this unusual neuropathy was to evaluate the efficacy of lesion resection and interposition grafting in its management. The charts of 15 patients operated on at LSU during a 15-year period with a pathological diagnosis of localized hypertrophic neuropathy were reviewed. Hypertrophic lesions were located on major named peripheral nerves of the extremities, distributed equally to the upper and lower extremities. Family history was negative for all patients, and entrapment or trauma, other than previous surgery, were unlikely by symptom location or history. Weakness was the most common presentation. The mean length of symptoms was 76 months. Atrophy, sensory loss, Tinel's sign, focal tenderness, and a mass were found in the majority of patients. Preoperative electrophysiological studies showed chronic denervational changes in all patients. At surgery, if no action potential or one of low amplitude was record...Continue Reading

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Citations

Jul 7, 2007·Neurosurgical Focus·Peter Gruen, David G Kline
Sep 21, 2007·Neurosurgery·Mattheos ChristoforidisAbolghassem Sepehrnia
Jul 27, 2012·Pediatric Radiology·Adrien RouxJean-Yves Gauvrit
Nov 28, 2018·Neurosurgery·Thomas J WilsonRobert J Spinner
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