PMID: 7922051Jul 1, 1994

Resection for extrahepatic recurrence of hepatocellular carcinoma

The British Journal of Surgery
C m LoJ Wong

Abstract

A total of 277 patients with hepatocellular carcinoma (HCC) underwent hepatic resection over a 20-year period. Twelve of 36 patients with recurrence confined to extrahepatic organs underwent surgical resection. There were no complications but one patient died in hospital from secondary intrahepatic recurrence. The 1-, 2- and 5-year survival rates for these 12 patients after hepatic resection were 92, 52 and 26 per cent respectively and were better than those of 24 patients who did not undergo resection for recurrence. The mean survival following resection for recurrent disease was 19.7 months and the longest survival time was nearly 8 years. Secondary recurrence after resection of metastases developed more commonly in the liver than in extrahepatic organs. Among the eight patients who survived for more than 4 months after the second operation, secondary recurrence developed in the liver and extrahepatic organs in eight and four patients respectively. In selected patients with isolated extrahepatic recurrence of HCC, surgery is effective in controlling extrahepatic disease and offers the only chance of long-term survival.

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Citations

Jan 1, 1991·World Journal of Surgery·E C LaiJ Wong
Jun 1, 1986·The British Journal of Surgery·N NagasueK Niimi
Jan 1, 1989·Cancer Chemotherapy and Pharmacology·N Nagasue, H Yukaya
Mar 1, 1988·The British Journal of Surgery·T KanematsuK Sugimachi
Jan 1, 1982·World Journal of Surgery·N W LeeG B Ong
Jan 1, 1984·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K OkudaK Ohnishi

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Abdominal Neoplasms
Malignant Bone Neoplasm
Liver Carcinoma
Survival Analysis
Sex Distribution
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Relapse
Malignant Neoplasm of Lung
Liver
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