Resection for lung cancer in the elderly patient

Thoracic Surgery Clinics
Elisabeth U DexterLeslie J Kohman

Abstract

Age is sometimes used as an excuse not to resect lung cancer. Nugent et al [10] noted that, although only 6% of patients younger than 45 years had stage I or II disease, 33% underwent surgical resection. In contrast, of the 33% of elderly patients who had stage I or II disease, only 6% underwent surgical resection. The elderly patients who are carefully selected for lung resection are undoubtedly stronger physiologically than others their same age. Patients with adequate predicted postoperative lung function, no contraindications from other medical problems, good performance status, and social support should be offered standard resection for early-stage NSCLC. Lung cancer resection in elderly patients is justified and has decreasing morbidity and mortality rates. Careful patient selection and operative planning are necessary, however. It is wise to have a diagnosis and staging done before the patient arrives in the operating suite. The surgeon should avoid extended resections when possible. In addition, elderly patients should be ambulated as soon as possible and adequate pain control should be ensured. Finally, the stage of the cancer and occurrence of cardiopulmonary complications are the main determinants of outcome.

References

Oct 1, 1976·The Annals of Thoracic Surgery·M M KirshH Sloan
Dec 1, 1990·The Annals of Thoracic Surgery·T IshidaK Sugimachi
Oct 1, 1985·The Thoracic and Cardiovascular Surgeon·H EbnerD Dragojević
Jan 1, 1986·CA: a Cancer Journal for Clinicians·A Baranovsky, M H Myers
Feb 1, 1988·The American Journal of Clinical Nutrition·D T DempseyG P Buzby
Aug 21, 1987·JAMA : the Journal of the American Medical Association·S Sherman, C E Guidot
Sep 1, 1987·Journal of Gerontology·L C DeMaria, H J Cohen
Feb 1, 1983·Journal of the American Geriatrics Society·D N Mohr
Nov 1, 1983·Journal of the American Geriatrics Society·W B ErshlerC J Greene
Nov 17, 1983·The New England Journal of Medicine·S KatzD S Greer
May 1, 1984·The American Review of Respiratory Disease·T P SmithR B George
Feb 1, 1981·Journal of the American Geriatrics Society·F F Holmes, E Hearne
Jan 1, 1994·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·K S NaunheimD R Judd
Jan 1, 1994·The Annals of Thoracic Surgery·T OsakiH Ueda
Apr 1, 1993·The Annals of Thoracic Surgery·W C FowlerS M Keller
Feb 1, 1996·The Thoracic and Cardiovascular Surgeon·G MassardG Morand
Jan 1, 1996·The European Respiratory Journal·R A Damhuis, P R Schütte
Jan 1, 1997·The Annals of Thoracic Surgery·W C NugentJ R Rigas
Mar 1, 1997·The Annals of Thoracic Surgery·S PagniR B Ponn
Mar 1, 1997·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·U MorandiR Lodi
Jul 1, 1997·The Annals of Thoracic Surgery·Y MizushimaM Kobayashi
Jun 17, 1998·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·P ThomasJ Deslauriers
Sep 3, 1998·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·S PagniR B Ponn
Aug 24, 1999·Current Opinion in Clinical Nutrition and Metabolic Care·F NourhashemiJ L Albarede
Oct 12, 1999·Scandinavian Cardiovascular Journal : SCJ·T SiorisS Mattila
Apr 6, 2000·The Annals of Thoracic Surgery·F BernetT P Carrel
Aug 2, 2000·The Annals of Thoracic Surgery·A P YimA A Arifi
Mar 28, 2001·The Annals of Thoracic Surgery·R T JagoeG J Gibson
Apr 18, 2001·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·I MikamiS Tanaka
Feb 22, 2002·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Kiyoshi KoizumiShigeo Tanaka
Dec 21, 2002·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Kazumichi YamamotoFrancisco París Romeu
Feb 6, 2003·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun

❮ Previous
Next ❯

Citations

Apr 25, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Yuh-Min ChenJacqueline Whang-Peng
Feb 25, 2000·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·S RicciP F Conte
Feb 10, 2006·Cancer Investigation·Katherine E Posther, David H Harpole
Sep 4, 2010·Seminars in Thoracic and Cardiovascular Surgery·Rafael S Andrade, Michael A Maddaus
Sep 3, 2008·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Toshio SuganeHirohiko Tsujii
Aug 8, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Maryska L G Janssen-HeijnenJan Willem W Coebergh
Jan 14, 2010·Thoracic Surgery Clinics·Holly M Holmes
Aug 7, 2013·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Trine OksholmTone Rustoen
Jul 30, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Beatriz Korc-GrodzickiRiccardo A Audisio
Feb 3, 2007·Current Opinion in Oncology·Lorenzo Spaggiari, Paolo Scanagatta
Jun 18, 2011·The American Surgeon·Paul D KiernanVivian Hetrick
Mar 8, 2006·Archives of Pathology & Laboratory Medicine·Alberto M Marchevsky

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.