Resection margins and local recurrences in breast cancer: Comparison between conventional and oncoplastic breast conserving surgery

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Laura NiinikoskiT J Meretoja

Abstract

This retrospective cohort study aims to compare surgical margins, reoperations and local recurrences after conventional or oncoplastic breast conservation surgery (BCS). Furthermore, we aim to investigate differences between various oncoplastic techniques. We reviewed 1800 consecutive patients with primary invasive breast cancer (N = 1707) or ductal carcinoma in situ (N = 93) who underwent BCS at Helsinki University Hospital between 2010 and 2012. Conventional BCS was performed in 1189 (66.1%) patients, oncoplastic BCS in 611 (33.9%). Various oncoplastic techniques were used. Patients with oncoplastic BCS had more often multifocal (p < 0.001), larger (p < 0.001), palpable tumours (p < 0.001) with larger resection specimens (p < 0.001). The amount of resected tissue varied substantially depending on the oncoplastic technique. Patients treated with oncoplastic BCS were younger (p < 0.001) and their tumours were more aggressive according to histological grade (p < 0.001), T-stage (p < 0.001), Ki-67 (p < 0.001) and lymph node status (p < 0.001). There was no difference, however, in surgical margins (p = 0.578) or reoperation rates (p = 0.430) between the groups. A total of 152 (8.4%) patients were reoperated because of insufficient...Continue Reading

Citations

Dec 21, 2019·Indian Journal of Surgical Oncology·Gianluca Franceschini, Riccardo Masetti
Mar 15, 2020·Archives of Gynecology and Obstetrics·Carolin MüllerStephanie Juhasz-Böss
Oct 30, 2021·The Cochrane Database of Systematic Reviews·Akriti NandaPankaj G Roy
Jan 11, 2022·Plastic and Reconstructive Surgery·Andrew A MaranoChristine H Rohde

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