PMID: 6138003Oct 1, 1983Paper

Resection of gastrinomas

Annals of Surgery
C W DeveneyL W Way


Exploratory laparotomy and a search for gastrinomas was performed in 52 patients with the Zollinger-Ellison syndrome (ZES). Gastrinoma tissue was resected in 11 patients (21%), 6 (12%) of whom appear to have been cured. After surgery, serum gastrin levels in these six patients have remained normal from 10 months to 10 years. In the 46 other patients, tumor was unresectable because of metastases or multiple primary tumors (21 patients; 40%) or inability to find the tumor at laparotomy (21 patients; 40%). Multiple pancreatic islet cell adenomata were found in six of seven patients with multiple endocrine neoplasia (MEN), indicating that patients with this condition usually have diffuse involvement of the pancreas. The results of CT scans correlated with findings at laparotomy in 13 of 16 patients. The smallest tumor detected by CT scans was 1 cm in diameter. CT technology is more accurate in finding gastrinomas now than in the past and has a useful role in preoperative evaluation. The possibility of resection should be seriously considered in every patient with Zollinger-Ellison syndrome. Abdominal CT scans, transhepatic portal venous sampling, and laparotomy should be used to find the tumor and to determine whether it is resecta...Continue Reading


Sep 1, 1978·Annals of Surgery·C W DeveneyL W Way
Dec 1, 1977·Annals of Internal Medicine·C W DeveneyL W Way
Aug 1, 1973·Archives of Surgery·J W HofmannS D WILSON
Jan 1, 1968·Vestnik khirurgii imeni I. I. Grekova·R I Poliak, A A Fisher
Apr 1, 1980·Radiology·N R DunnickD M McCarthy
Jan 1, 1983·Annals of Internal Medicine·R T JensenM J Collen
Jul 1, 1983·American Journal of Surgery·C W DeveneyL W Way
Jun 12, 1980·The New England Journal of Medicine·D M McCarthy
Mar 1, 1982·Missouri Medicine·J B Marshall
Nov 1, 1982·Annals of Surgery·I M ModlinD Albert


Jan 1, 1991·Virchows Archiv. A, Pathological Anatomy and Histopathology·D SantiniG N Martinelli
Aug 1, 1984·World Journal of Surgery·N ThompsonT Mervak
Jul 1, 1993·World Journal of Surgery·F StadilF Efsen
Dec 1, 1984·World Journal of Surgery·N Thompson, F E Eckhauser
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Dec 4, 2002·Clinical Endocrinology·J J O TurnerK Meeran
Aug 26, 1999·The New England Journal of Medicine·J A NortonR T Jensen
Feb 17, 1984·Wiener klinische Wochenschrift·H D Becker
May 1, 1987·Annals of Surgery·S B VogelE R Woodward
Jan 1, 1990·Annals of Surgery·T J HowardE Passaro
Jan 1, 1994·Clinical Endocrinology·P J HammondS R Bloom
Jan 1, 1995·Annual Review of Medicine·J B Meko, J A Norton
Jan 1, 1991·World Journal of Surgery·J A Norton, R T Jensen
Apr 1, 1988·Pathology, Research and Practice·G Klöppel, P U Heitz
Feb 1, 1994·Current Problems in Surgery·J A Norton
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Jun 1, 1990·Current Problems in Surgery·E MozellT M O'Dorisio
Feb 1, 1990·American Journal of Surgery·T J HowardE Passaro
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