Residential Eviction and Risk of Detectable Plasma HIV-1 RNA Viral Load Among HIV-Positive People Who Use Drugs

AIDS and Behavior
Mary Clare KennedyM-J Milloy

Abstract

We examined the relationship between residential eviction and exhibiting detectable plasma HIV-1 RNA viral load (VL) among a prospective cohort of antiretroviral therapy (ART)-exposed HIV-seropositive people who use illicit drugs (PWUD) in Vancouver, Canada. We used multivariable generalized estimating equations to estimate the effect of residential eviction on detectable VL and examine ART adherence as a mediating variable. Between June 2007 and May 2014, 705 ART-exposed participants were included in the study, among whom 500 (70.9 %) experienced at least one period of detectable VL. In a time-updated multivariable model, eviction independently increased the odds of detectable VL among those who were homeless [adjusted odds ratio (AOR) = 2.25; 95 % confidence interval (CI) 1.18-4.29] as well as not homeless (AOR = 1.76; 95 % CI 1.17-2.63) post eviction. The results of mediation analyses suggest that this association was mediated by incomplete ART adherence. These findings suggest the need for further development and evaluation of interventions to prevent evictions and promote ART adherence among PWUD facing eviction.

References

Dec 1, 1993·American Journal of Epidemiology·G Maldonado, S Greenland
Jul 2, 1997·JAMA : the Journal of the American Medical Association·D BangsbergA R Moss
Aug 26, 1998·JAMA : the Journal of the American Medical Association·S A StrathdeeR S Hogg
Jul 21, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·G M LucasR D Moore
Jul 20, 2002·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Spencer LiebGayle McLaughlin
Apr 8, 2003·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Anita PalepuJulio S G Montaner
Jun 16, 2005·Social Science & Medicine·Tim RhodesSteffanie A Strathdee
May 3, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Amy KnowltonUNKNOWN INSPIRE Team
Feb 3, 2007·American Journal of Public Health·Robin PhinneyKristin Seefeldt
May 19, 2007·AIDS and Behavior·Alison ScottLori Leonard
Aug 5, 2008·JAMA : the Journal of the American Medical Association·Evan WoodJulio S G Montaner
Aug 22, 2009·American Journal of Public Health·Craig Evan Pollack, Julia Lynch
Jul 24, 2010·Lancet·Steffanie A StrathdeeCatherine A Hankins
Mar 17, 2011·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Anita PalepuEvan Wood
Jul 20, 2011·The New England Journal of Medicine·Myron S CohenUNKNOWN HPTN 052 Study Team
Sep 13, 2012·Current HIV/AIDS Reports·M-J MilloyEvan Wood

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Citations

Aug 2, 2018·Current Infectious Disease Reports·M Eugenia Socias, M-J Milloy
Jul 22, 2019·AIDS and Behavior·Elise D RileyAdam W Carrico
Oct 27, 2018·Sexually Transmitted Diseases·Jacky M Jennings, Kathryn M Leifheit
Apr 24, 2020·AIDS and Behavior·Eunhee ParkLaramie R Smith
Jan 9, 2021·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Emily A BenferDanya E Keene
Mar 2, 2021·JAMA Pediatrics·Gracie Himmelstein, Matthew Desmond
May 11, 2020·The International Journal on Drug Policy·Taylor FlemingRyan McNeil
Feb 4, 2021·Health & Social Care in the Community·Corey HazekampMartin MacDowell
Jan 18, 2021·American Journal of Epidemiology·Gabriel L SchwartzMariana C Arcaya
Aug 3, 2021·Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals·Elinor ChisholmPhilippa Howden-Chapman

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