PMID: 8602667Feb 1, 1996Paper

Residual block after mivacurium with or without edrophonium reversal in adults and children

Anesthesiology
D R BevanJ C Bevan

Abstract

The rapid recovery from mivacurium- induced neuromuscular block has encouraged omission of its reversal. The purpose of this study was to determine, in children and in adults, whether failure to reverse mivacurium neuromuscular block was associated with residual neuromuscular block on arrival in the postanesthesia care unit. In 50 children, aged 2-12 yr, and 50 adults, aged 20-60 yr, anesthesia was induced and maintained with propofol and fentanyl, and neuromuscular block was achieved by an infusion of mivacurium, to maintain one or two visible responses to train-of-four (TOF) stimulation of the ulnar nerve. At the end of surgery, mivacurium infusion was stopped, and 10 min later, reversal was attempted with saline or 0.5 mg x kg(-1) edrophonium by random allocation. On arrival in the postanesthesia care unit, a blinded observer assessed patients clinically and by stimulation of the ulnar nerve with a Datex electromyogram in the uncalibrated TOF mode. Children arrived in the postanesthesia care unit 8.2 +/- 3-4 min after reversal of neuromuscular block and showed no sign of weakness, either clinically or by TOF stimulation. Although TOF ratio was greater in children who had received edrophonium (1.00 +/- 0.05 vs. 0.93 +/- 0.01,...Continue Reading

References

Jun 1, 1979·Anesthesiology·J Viby-MogensenH Ording
Mar 8, 1976·JAMA : the Journal of the American Medical Association·R M RossenE W Hancock
Apr 1, 1991·Anesthesia and Analgesia·M R BaxterD R Bevan
Oct 1, 1990·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·O A Meretoja, R Gebert
Mar 1, 1990·British Journal of Anaesthesia·S S GillF Donati
Feb 1, 1989·Anesthesiology·N G GoudsouzianJ J Savarese
Oct 1, 1988·British Journal of Anaesthesia·M J KingA R Deacock
Sep 1, 1986·Canadian Anaesthetists' Society Journal·R K Mirakhur
Feb 1, 1986·Anaesthesia and Intensive Care·G H Beemer, P Rozental
Dec 1, 1983·Anesthesia and Analgesia·N G GoudsouzianM Gionfriddo
Oct 1, 1984·Anesthesiology·D M FisherR D Miller
Aug 1, 1993·Anesthesia and Analgesia·E J Pantuck
Apr 1, 1993·Acta Anaesthesiologica Scandinavica·D OstergaardJ Viby-Mogensen
Jan 1, 1993·Anesthesia and Analgesia·R S PetersenE R Ashwood

❮ Previous
Next ❯

Citations

Mar 17, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·H ViitanenP Annila
Aug 1, 1997·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·M R LessardJ F Rouillard
Jun 17, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·D R Bevan
Oct 4, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Thomas M Hemmerling, François Donati
Dec 13, 2002·Journal of Clinical Anesthesia·Xiaoguang ChenEve Norel
Oct 24, 2002·British Journal of Anaesthesia·C McCaulA J McShane
Dec 19, 2002·British Journal of Anaesthesia·J G LaffeyA J McShane
Jan 1, 1997·Acta Anaesthesiologica Scandinavica. Supplementum·D Bevan
Sep 20, 1997·Anesthesia and Analgesia·J C Ballantyne, Y Chang
Mar 11, 1999·Anesthesia and Analgesia·C A LienJ J Savarese
Oct 26, 2005·Anesthesia and Analgesia·Ching-Rong ChengChristian C Apfel
Jan 24, 2006·Anesthesia and Analgesia·Guy CammuThierry Deloof
Jul 25, 2013·Anesthesia and Analgesia·Mohamed NaguibHal R Arkes
May 13, 2011·Der Anaesthesist·B S von Ungern-Sternberg
Aug 1, 1997·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·L McEwinD R Bevan
May 1, 1997·Anesthesiology·D R Bevan, J C Bevan
Sep 30, 2005·Anesthesiology·Francois GijsenberghThijs van Iersel
Jan 5, 2002·European Journal of Anaesthesiology. Supplement·T Fuchs-Buder, T Mencke
Feb 5, 2014·Anesthesiology Clinics·Britta S von Ungern-Sternberg
Jan 10, 2002·Anesthesiology Clinics of North America·D R Bevan
Mar 9, 2005·Acta Anaesthesiologica Scandinavica·S R ArainT J Ebert
Feb 19, 2009·Anaesthesia·J E Caldwell, R D Miller
Jan 4, 2012·Paediatric Anaesthesia·Nigel D HamiltonBritta S von Ungern-Sternberg
Jul 26, 2005·Annales Françaises D'anesthèsie Et De Rèanimation·M Beaussier, M A Boughaba
Apr 9, 2011·Revista brasileira de anestesiologia·Camila Machado de SouzaMaria Angela Tardelli
Jan 16, 2014·Korean journal of anesthesiology·Sangseok Lee
Aug 15, 2017·The Cochrane Database of Systematic Reviews·Ana-Marija HristovskaArash Afshari
May 6, 2014·The Cochrane Database of Systematic Reviews·Lei YangDongHao Lu
Oct 13, 2009·The Cochrane Database of Systematic Reviews·Amir AbrishamiFrances Chung
May 16, 2000·Anesthesia and Analgesia·David R Bevan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.