PMID: 9163633May 1, 1997Paper

Residual effect of nCPAP applied for part of the night in patients with obstructive sleep apnoea

The European Respiratory Journal
V HersD O Rodenstein

Abstract

The aim of the present study was to assess whether nasal continuous positive airway pressure (nCPAP) treatment, applied for only a few hours at the beginning of the night, has any residual effect on sleep and breathing during the ensuing hours of unassisted sleep in patients with obstructive sleep apnoea syndrome (OSAS). In 27 patients with newly-diagnosed OSAS, effective nCPAP was applied during the first part of the night and then withdrawn. Polysomnographic parameters after nCPAP withdrawal were compared with those of the corresponding part of the diagnostic polysomnography performed a few days or weeks before and with those of the first part of night on nCPAP. After 255+/-63 (mean+/-SD) min of sleep with normalization of sleep and breathing parameters under nCPAP, there was partial improvement of OSAS severity during the remaining 124+/-56 min of nocturnal sleep without treatment; mean oxygen saturation, desaturation index (equivalent to the apnoea/hypopnoea index) and movement arousal index all improved significantly with respect to the diagnostic night (p=0.001). This improvement was not accounted for by a change in sleep architecture. We conclude that there is an improvement in severity of obstructive sleep apnoea syndro...Continue Reading

Citations

Apr 25, 2003·Sleep & Breathing = Schlaf & Atmung·Melanie K MeansRodney A Radtke
Nov 28, 2012·Sleep & Breathing = Schlaf & Atmung·Filipa Soares PiresJoão Almeida
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Jul 20, 2011·Current Treatment Options in Neurology·Roop KawNancy A Collop
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Jun 6, 2013·Expert Review of Respiratory Medicine·Eusebi ChinerFerran Barbé

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