Residual Effects of Sleep Medications Are Commonly Reported and Associated with Impaired Patient-Reported Outcomes among Insomnia Patients in the United States

Sleep Disorders
Timothy Fitzgerald, Jeffrey Vietri

Abstract

Study Objective. To measure the association of symptoms attributed to residual effects of sleep medication (e.g., drowsiness, difficulty concentrating, and impaired memory) on self-reported functioning and satisfaction with these medications. Methods. Individuals using prescription medications for insomnia were invited to complete an Internet-based survey. Respondents were compared according to the presence of self-reported residual effects; relationships between severity of these effects and outcomes were modeled using regression. Measures included the Brief Insomnia Questionnaire, Work Productivity and Activity Impairment Questionnaire, and SATMED-Q. Subgroup analyses were conducted with patients aged ≥65 years. Approximately 80% reported experiencing ≥1 residual effect. The severity of residual effects was associated with increased residual effect-related work impairment, including absenteeism (RR = 1.46, p < 0.001), presenteeism (RR = 1.12, p < 0.001), overall work impairment (RR = 1.13, p < 0.001), and nonwork activity impairment (RR = 1.11, p < 0.001). More severe residual symptoms were also associated with increased difficulty in home management (Beta = .31, p < 0.001), ability to work (Beta = .31, p < 0.001), social rel...Continue Reading

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Citations

Dec 14, 2016·Open Forum Infectious Diseases·Gianna PeraltaLisa Pascopella
Sep 2, 2018·BMJ Case Reports·Muhammad Ahsan SaeedMarilou Corpuz
Dec 23, 2016·Public Health Reports·Frances TyrrellStephanie Johnston
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Dec 4, 2020·Journal of Cancer Survivorship : Research and Practice·Stephen Rajan SamuelJustin William Leslie Keogh
Apr 4, 2021·International Journal of Environmental Research and Public Health·Jesús López-Torres LópezGemma Blázquez Abellán

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Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

SATMED

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