Abstract
After an acute pulmonary embolism (PE), the complete resolution of thromboemboli may not be routinely achieved. The rate of persistence may depend on the time and the diagnostic technique used for evaluation. Patients were diagnosed with acute PE by means of computed tomography angiography (CTA). While they were receiving anticoagulant therapy, a second CTA was used to explore the rate of persistence of residual thromboemboli. During the initial episode, the plasma levels of Troponin I and natriuretic peptide, patient demographics, and hemodynamic and gas exchange data were evaluated as risk factors for persistence of pulmonary thromboemboli. In this study 166 patients were diagnosed. A second CTA was not made in 46 (28%) patients for different reasons. In 120 (72%) patients a second CTA was made 4.5 [SD2.34] months after the initial episode (range 2-12 months). Complete clearance of thrombi occurred in 89 (74%, 95% CI 65-81) patients. Residual thrombi remained in 31 (26%, 95% CI 18-34) patients. In 6%, 13% and 81% of the patients the size of the residual thrombi was greater, similar to and smaller than initially diagnosed, respectively. The risk factors for residual thrombi included the thrombotic burden (OR 1.95), the alveola...Continue Reading
References
Jan 1, 1988·European Journal of Nuclear Medicine·K Hvid-JacobsenO J Hartling
Apr 1, 1997·Radiology·M Remy-JardinA Duhamel
May 25, 2001·AJR. American Journal of Roentgenology·S D QanadliP Lacombe
Nov 2, 2004·American Journal of Respiratory and Critical Care Medicine·Jean-Paul RichaletJérémy Cornolo
Apr 22, 2005·British Journal of Haematology·Gabriela Cesarman-Maus, Katherine A Hajjar
Apr 23, 2005·Radiology·Rutger W van der MeerMenno V Huisman
May 13, 2005·Chest·Marc HeinrichHans-Joachim Schäfers
Jan 21, 2006·Chest·Mathilde NijkeuterMenno V Huisman
May 23, 2006·AJR. American Journal of Roentgenology·Eric N C Milne
Sep 16, 2006·Medicine·Massimo MiniatiCarlo Giuntini
Jul 4, 2007·Circulation·Cecilia BecattiniGiancarlo Agnelli
Jul 20, 2007·JAMA : the Journal of the American Medical Association·Andrew J EinsteinSanjay Rajagopalan
May 26, 2009·Chest·David JiménezRoger D Yusen
Dec 8, 2009·American Journal of Respiratory and Critical Care Medicine·Frederikus A KlokMenno V Huisman
Dec 10, 2009·Radiologic Clinics of North America·Jean Kuriakose, Smita Patel
Jul 7, 2010·European Journal of Internal Medicine·J L Alonso-MartínezM A Urbieta Echezarreta
Sep 24, 2010·The New England Journal of Medicine·Gregory J del Zoppo, Brian T Hawkins
Oct 23, 2010·International Heart Journal·Kosaku GotoMasahiko Kurabayashi
Citations
Aug 30, 2014·Blood Reviews·F A KlokS Konstantinides
Jun 16, 2015·European Journal of Radiology·M MeysmanJ de Mey
Jul 31, 2014·Thrombosis Research·Donatella LamiDomenico Prisco
Oct 21, 2016·Vascular Medicine·Akhilesh K SistaJeffrey A Kline
Jan 23, 2018·World Journal of Radiology·John L NosherVyacheslav Gendel
Jan 30, 2018·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Jan MrozekPavel Jansa
Sep 8, 2019·Journal of Thrombosis and Thrombolysis·Ming Sheng LimSanjeev Chunilal
Feb 14, 2020·The Clinical Respiratory Journal·Jun AnChen Wang
Oct 21, 2015·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Keum-Ju ChoiWon-Kee Lee
Oct 6, 2020·Pulmonary Circulation·Daniel LachantR James White
Oct 14, 2017·Journal of Thrombosis and Thrombolysis·Jingluan WangJingjing Sui
Feb 7, 2021·Seminars in Respiratory and Critical Care Medicine·Gudula J A M BoonFrederikus A Klok
Feb 6, 2021·Clinics in Chest Medicine·Irene M LangNika Skoro-Sajer
Mar 5, 2021·Thrombosis Research·Øyvind JervanWaleed Ghanima
Jan 7, 2020·Archivos de bronconeumología·Purificación RamírezJoan Albert Barberà