Residual pulmonary thromboemboli after acute pulmonary embolism

European Journal of Internal Medicine
J L Alonso-MartínezHelena Gómez Herrero

Abstract

After an acute pulmonary embolism (PE), the complete resolution of thromboemboli may not be routinely achieved. The rate of persistence may depend on the time and the diagnostic technique used for evaluation. Patients were diagnosed with acute PE by means of computed tomography angiography (CTA). While they were receiving anticoagulant therapy, a second CTA was used to explore the rate of persistence of residual thromboemboli. During the initial episode, the plasma levels of Troponin I and natriuretic peptide, patient demographics, and hemodynamic and gas exchange data were evaluated as risk factors for persistence of pulmonary thromboemboli. In this study 166 patients were diagnosed. A second CTA was not made in 46 (28%) patients for different reasons. In 120 (72%) patients a second CTA was made 4.5 [SD2.34] months after the initial episode (range 2-12 months). Complete clearance of thrombi occurred in 89 (74%, 95% CI 65-81) patients. Residual thrombi remained in 31 (26%, 95% CI 18-34) patients. In 6%, 13% and 81% of the patients the size of the residual thrombi was greater, similar to and smaller than initially diagnosed, respectively. The risk factors for residual thrombi included the thrombotic burden (OR 1.95), the alveola...Continue Reading

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Citations

Jan 23, 2018·World Journal of Radiology·John L NosherVyacheslav Gendel
Jan 30, 2018·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Jan MrozekPavel Jansa
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Feb 7, 2021·Seminars in Respiratory and Critical Care Medicine·Gudula J A M BoonFrederikus A Klok
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Mar 5, 2021·Thrombosis Research·Øyvind JervanWaleed Ghanima
Jan 7, 2020·Archivos de bronconeumología·Purificación RamírezJoan Albert Barberà

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