PMID: 12465701Dec 6, 2002Paper

Resistance amongst yeasts isolated from the oral cavities of patients with advanced cancer

Palliative Medicine
Andrew N DaviesDavid Beighton

Abstract

The aim of this study was to determine the prevalence of in vitro resistance amongst yeasts isolated from the oral cavities of patients with advanced cancer. The National Committee for Clinical Laboratory Standards' broth microdilution method was used to determine the sensitivities to fluconazole, itraconazole, ketoconazole, and nystatin, whilst the Etest method was used to determine the sensitivity to amphotericin B. The prevalence of in vitro resistance was: amphotericin B, 2%; fluconazole, 8%; itraconazole, 22%; ketoconazole, 7%; nystatin, 0%. Moreover, 28% of the yeasts was resistant to one or more of the azole group of anti-fungal drugs. The results of this study suggest that azole resistance may become a clinical problem in palliative care.

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Citations

Oct 29, 2004·Oral Oncology·Niroshani S SoysaA N Ellepola
Feb 5, 2008·Journal of Pain and Symptom Management·Andrew N DaviesVictoria C Stevens
Mar 11, 2006·Oral Oncology·Andrew N DaviesDavid Beighton
Sep 24, 2013·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Paula Volpato SanitáCarlos Eduardo Vergani
Oct 7, 2010·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Silke SchelenzPaul R Hunter
Feb 16, 2006·Journal of Medical Microbiology·Carlos E B LinaresMaria R C Schetinger
Apr 5, 2005·Scandinavian Journal of Infectious Diseases·Lars StolleJohnny Keller
Mar 15, 2005·Scandinavian Journal of Infectious Diseases·Erja ChryssanthouMagnus Björkholm

Related Concepts

Antibiotics, Antifungal
Candida utilis
Oral Candidiasis
Malignant Neoplasms
Palliative Surgery
Antibiotic Resistance, Fungal

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