Resistance and Virulence Features of Bacteroides spp. Isolated from Abdominal Infections in Romanian Patients

Pathogens
Gabriela Roxana PricopEugenia Bezirtzoglou

Abstract

Anaerobic bacteria are predominant residents of the normal microbiota of the skin and mucous membranes but are also known to be associated with a number of human infections including peritonitis, appendicitis, abscesses, ulcers and wound infections. Herein, we investigate the antibiotic resistance profiles as well as the genetic support of antibiotic resistance and virulence determinants of anaerobic bacteria isolated from intra-abdominal infections. The study was performed on 198 Romanian patients from which different clinical samples were taken intra-operatory and sent for microbiological analyses. From the total number of isolated strains, a subset of 75 Bacteroides spp. were selected and further investigated for antibiotic resistance and virulence features, at phenotypic and genetic level. Our results obtained through the analysis of a significant number of Bacteroides strains could shed light on the virulence potential and mechanisms by which anaerobic bacteria can cause endogenous infections.

References

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Jul 18, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·N Ulger ToprakG Soyletir
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May 12, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·E NagyUNKNOWN ESCMID Study Group on Antimicrobial Resistance in Anaerobic Bacteria
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Jan 6, 2018·Infectious Diseases·Károly Péter SárváriEdit Urbán
Apr 8, 2018·Microbiological Research·Reza GhotaslouMohammad Yousef Memar

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Methods Mentioned

BETA
PCRs
PCR
electrophoresis

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