Resistance Exercise's Ability to Reverse Cancer-Induced Anabolic Resistance

Exercise and Sport Sciences Reviews
Ryan N MontalvoJames A Carson

Abstract

Skeletal muscle has the dynamic capability to modulate protein turnover in response to anabolic stimuli, such as feeding and contraction. We propose that anabolic resistance, the suppressed ability to induce protein synthesis, is central to cancer-induced muscle wasting. Furthermore, we propose that resistance exercise training has the potential to attenuate or treat cancer-induced anabolic resistance through improvements in oxidative metabolism.

References

Nov 5, 2002·Nature Reviews. Cancer·Michael J Tisdale
Jul 12, 2007·The Biochemical Journal·Helen L EleyMichael J Tisdale
Aug 7, 2007·BMC Cancer·Jeffrey S OtisJay H Williams
Dec 7, 2007·American Journal of Physiology. Endocrinology and Metabolism·Hans C DreyerBlake B Rasmussen
Oct 17, 2008·Physiological Reviews·Scott K Powers, Malcolm J Jackson
May 3, 2011·Current Aging Science·Christopher S Fry, Blake B Rasmussen
Sep 29, 2011·The Journal of Physiology·Craig A GoodmanTroy A Hornberger
Apr 6, 2012·Journal of Cachexia, Sarcopenia and Muscle·Melissa J PuppaJames A Carson
May 16, 2012·Journal of Cachexia, Sarcopenia and Muscle·Edgar L DillonMelinda Sheffield-Moore
Jun 1, 2012·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Aaron WinterStéphanie Chevalier
Oct 5, 2012·The American Journal of Clinical Nutrition·John P WilliamsMichael J Rennie
Oct 24, 2012·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Christopher S FryBlake B Rasmussen
Dec 15, 2012·Journal of Cachexia, Sarcopenia and Muscle·Douglas W GouldGeorge S Metsios
Feb 12, 2013·Cell Metabolism·Brendan Egan, Juleen R Zierath
Mar 16, 2013·Current Opinion in Clinical Nutrition and Metabolic Care·Yichen Wang, Jeffrey E Pessin
Mar 23, 2013·The FEBS Journal·Stefano SchiaffinoMarco Sandri
Mar 28, 2013·American Journal of Physiology. Endocrinology and Metabolism·James P WhiteJames A Carson
Aug 24, 2013·The American Journal of Clinical Nutrition·Carla M PradoVickie E Baracos
Oct 17, 2013·PloS One·Cameron J MitchellStuart M Phillips
Mar 14, 2014·Redox Report : Communications in Free Radical Research·Shaun Mason, Glenn D Wadley
Jun 25, 2014·Mayo Clinic Proceedings·Justin P HardeeSteven N Blair
Nov 6, 2014·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Alisdair J MacDonaldTom Preston
Dec 30, 2014·Medicine and Science in Sports and Exercise·Craig PorterBlake B Rasmussen
Jan 16, 2015·Cell Cycle·Masahiro MoritaIvan Topisirovic
Sep 25, 2015·Journal of Cachexia, Sarcopenia and Muscle·David Pj van DijkCornelis Hc Dejong
Oct 24, 2015·Journal of Applied Physiology·Justin P HardeeJames A Carson
Aug 24, 2016·Physiological Reports·Kohei KidoSatoshi Fujita
Aug 9, 2017·Oxidative Medicine and Cellular Longevity·Brandon N VanderVeenJames A Carson
Sep 19, 2017·Molecular Cell·Masahiro MoritaNahum Sonenberg
Dec 8, 2017·Journal of Cachexia, Sarcopenia and Muscle·Justin P HardeeJames A Carson
Jan 30, 2018·Oxidative Medicine and Cellular Longevity·Justin P HardeeJames A Carson
Feb 2, 2018·Current Opinion in Critical Care·Robert W MortonStuart M Phillips
Mar 6, 2018·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S Antoun, B Raynard
Feb 1, 2018·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S Antoun, B Raynard

❮ Previous
Next ❯

Citations

Oct 28, 2019·Cancer Causes & Control : CCC·Mario RedondoIsabel Prieto
Sep 29, 2020·Frontiers in Physiology·Brandon N VanderVeenJames A Carson
Aug 14, 2018·Current Opinion in Supportive and Palliative Care·Ryan N MontalvoJames A Carson
Apr 20, 2021·Integrative Cancer Therapies·Nathan H ParkerMatthew H G Katz
Mar 19, 2021·Medicine and Science in Sports and Exercise·Camila S PadilhaRafael Deminice
Aug 27, 2021·Metabolites·Alessandra RenziniLuca Madaro
Aug 28, 2021·International Journal of Molecular Sciences·Hiroki NishikawaKazuhide Higuchi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Cachexia

Cardiac cachexia is a syndrome associated with the progressive loss of muscle and fat mass. It most commonly affects patients with heart failure and can significantly decrease the quality of life and survival in these patients. Here is the latest research on cardiac cachexia.

Cachexia & Brown Fat

Cachexia is a condition associated with progressive weight loss due to severe illness. In cancer patients, it is proposed to occur as a result of tumor-induced energy wasting. Several proteins have been implicated in browning and depletion of white adipose tissue. Here is the latest research on cachexia and brown fat.

Biomechanics

Biomechanics examines the generation of internal forces within the body and investigates the effects and control of forces that act on or are produced on tissues. Here are the latest discoveries.