Resistance of callose synthase activity to free fatty acid inhibition as an indicator of Fusarium head blight resistance in wheat

Plant Signaling & Behavior
Dorothea EllingerChristian A Voigt

Abstract

The fungal pathogen Fusarium graminearum is the causal agent of Fusarium head blight (FHB); a devastating crop disease resulting in heavy yield losses and grain contamination with mycotoxins. We recently showed that the secreted lipase FGL1, a virulence factor of F. graminearum, targets plant defense-related callose biosynthesis during wheat head infection. This effector-like function is based on a FGL1-mediated release of polyunsaturated free fatty acids (FFA) that can inhibit callose synthase activity. The importance of FGL1 in successful wheat head colonization was demonstrated in FGL1 disruption mutants (Δfgl1), where infection was restricted to directly inoculated spikelets and accompanied by strong callose deposition in the spikelet's phloem. The application of polyunsaturated FFA to Δfgl1-infected spikelets prevented callose deposition in the phloem and partially restored wheat head colonization.   The comparative analysis of 3 wheat cultivars revealed that the level of resistance to FHB correlated with resistance to FFA-dependent inhibition of callose biosynthesis. Therefore, resistance of callose biosynthesis to FFA inhibition might be used as marker and/or direct target in the breeding of FHB-resistant wheat cultivars.

References

Jul 1, 1995·Molecular Plant-microbe Interactions : MPMI·R H ProctorS P McCormick
Apr 3, 2003·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·I A del BlancoS F Kianian
Apr 22, 2005·The Plant Journal : for Cell and Molecular Biology·Christian A VoigtSiegfried Salomon
Nov 17, 2006·Nature·Jonathan D G Jones, Jeffery L Dangl
Apr 5, 2012·Molecular Plant Pathology·Ralph DeanGary D Foster
Dec 1, 1997·Plant Disease·Marcia McMullenDale Gallenberg

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