Resistance, serotype and genetic diversity of Streptococcus pneumoniae-resistant strains isolated in the West Pomerania region of Poland in the years 2001-2005.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
Monika M Nowosiad, Stefania T Giedrys-Kalemba

Abstract

The aim of this study was to analyse the resistance patterns, serotypes and genetic diversity of Streptococcus pneumoniae-resistant strains isolated in the West Pomerania region of Poland. They were clinical isolates obtained during a 5-year study (2001-2005) mainly from ambulatory patients with upper respiratory tract infections. The strains showed resistance to 8 out of 9 tested antibiotics (except vancomycin) and 53.8% of the strains were multidrug-resistant (MDR). The increase over time in the number of MDR strains and in resistance degrees was not statistically significant. Resistance to cotrimoxazole was the most frequent (86.7%). Penicillin nonsusceptibility was shown in 38% of the strains and resistance to macrolides in 36.7% of the strains, mainly of MLS(B) phenotype (94.1%). A significant resistance increase was only observed for beta-lactam antibiotic. The population of S. pneumoniae-resistant strains in our region presented 31 resistance patterns, 13 serotypes and a high genetic diversity-70 pulse field gel electrophoresis (PFGE) profiles have been described: 44 of them were unique and 26 clusters consisted of 2 to 30 strains similar by more than 87%. Cluster I, grouping 30 strains of similar resistant patterns (TSH...Continue Reading

References

Apr 1, 1990·Clinical Microbiology Reviews·K P Klugman
Oct 20, 1993·JAMA : the Journal of the American Medical Association·J C ButlerR R Facklam
Oct 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P C AppelbaumM R Jacobs
Jul 1, 1997·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·K G Kristinsson
Jan 1, 1997·Society for Applied Bacteriology Symposium Series·C G DowsonM Yeo
Apr 29, 1999·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A Hoefnagels-SchuermansW E Peetermans
May 15, 1999·Journal of Clinical Microbiology·K OverwegW Hryniewicz
Aug 4, 1999·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·R HakenbeckD Zähner
Jan 5, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·W P HausdorffG R Siber
Oct 26, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M A KelleyM S Cohen
Nov 13, 2002·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Joshua P Metlay, Daniel E Singer
Jan 31, 2003·The Journal of Antimicrobial Chemotherapy·A FenollJ Casal
Apr 23, 2003·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Ewa SadowyWaleria Hryniewicz
Jun 25, 2003·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Anna Skoczyńska, Waleria Hryniewicz
Oct 22, 2003·The Pediatric Infectious Disease Journal·Michael R Jacobs, Candice E Johnson
Jan 21, 2006·International Journal of Antimicrobial Agents·Katarzyna Dzierzanowska-FangratKrzysztof Trzciński
Jan 11, 2007·Antimicrobial Agents and Chemotherapy·Radosław IzdebskiWaleria Hryniewicz
Mar 16, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A SkoczyńskaW Hryniewicz

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Citations

Oct 22, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·W KrzyściakD Kościelniak
Nov 13, 2010·Journal of Medical Microbiology·Malek RachdiSaida Ben Redjeb
Dec 18, 2010·Expert Review of Vaccines·E David G McIntosh, Ralf R Reinert

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