Resistance to Schistosoma mansoni by transplantation of APO Biomphalaria tenagophila

Parasite Immunology
Luciene BarbosaPaulo Marcos Zech Coelho

Abstract

Transplantation of the haematopoietic organ from Biomphalaria tenagophila (Taim strain, RS, Brazil), resistant to Schistosoma mansoni, to a highly susceptible strain (Cabo Frio, RJ, Brazil) of the same species, showed in the recipient snails resistance against the trematode, when a successful transplant occurred. The success of transplantation could be confirmed by a typical molecular marker of the Taim strain in haemocytes of the recipients (350 bp detected by PCR-RFLP). The recipient snails which did not present the donor marker in haemocytes (unsuccessful transplantation) were infected with the parasite. The use of an atoxic modelling clay for closing the hole in the transplantation site reduced significantly the mortality caused by bleeding after transplantation procedures.

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Citations

Nov 26, 2015·Developmental and Comparative Immunology·E A PilaP C Hanington
Jul 20, 2012·Journal of Parasitology Research·D Negrão-CorrêaP M Z Coelho
Jan 8, 2016·Trends in Parasitology·Alessio GiannelliDomenico Otranto
Jan 19, 2013·Revista Do Instituto De Medicina Tropical De São Paulo·Florence Mara RosaPaulo Marcos Zech Coelho
Aug 2, 2012·Memórias do Instituto Oswaldo Cruz·Samaly Dos Santos Souza, Zilton Araújo Andrade
Apr 7, 2009·Brazilian Journal of Biology = Revista Brasleira De Biologia·S M AllegrettiE M Zanotti-Magalhães
Aug 20, 2010·Memórias do Instituto Oswaldo Cruz·Liana K Jannotti-PassosOmar S Carvalho
Aug 21, 2009·Nature·Arbora ResulajMichael N Shadlen
Nov 12, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Aristeu Silva-NetoConsuelo Latorre Fortes-Dias

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