Resistance training decreases plasma levels of adipokines in postmenopausal women.

Scientific Reports
Liam J WardWei Li

Abstract

Physical inactivity and the onset of menopause increase the risk of cardiovascular disease amongst postmenopausal women. We aim to investigate the effect of resistance training (RT) on plasma levels of selected cytokines, adipokines, myokines, and sex hormones in postmenopausal women with vasomotor symptoms. This was a sub-study of a randomised controlled trial investigating the effects of RT on vasomotor symptoms in postmenopausal women. Women were randomised to join a 15-week RT program (n = 26) or remain sedentary as control (n = 29). Venous blood samples were taken at week-0 and week-15 for all participants. Enzyme-linked immunosorbent assays and multiple bead assays were used to measure cytokines, adipokines, myokines, and sex hormones in plasma. Plasma measurements of 16 of 33 analytes were within detectable limits. After adjusting for good compliance in the RT group (58% of RT participants), after 15 weeks, significantly lower plasma levels of adiponectin (p < 0.001), lipocalin-2 (p < 0.01) and resistin (p = 0.04) were found. Comparing control and RT women, using change-over-time values, significant increases in median testosterone and sex hormone binding globulin levels were seen in RT women. RT intervention lowers the ...Continue Reading

References

Jun 11, 2002·British Journal of Sports Medicine·Y OgumaI-M Lee
Feb 16, 2005·Circulation·Muredach P ReillyDaniel J Rader
Sep 9, 2006·European Heart Journal·Hwee TeohSubodh Verma
Mar 8, 2007·American Journal of Physiology. Endocrinology and Metabolism·Jaak Jürimäe, Toivo Jürimäe
Jan 19, 2008·Menopause : the Journal of the North American Menopause Society·Courtney D PerryUlrike Genschel
Mar 19, 2008·Menopause : the Journal of the North American Menopause Society·Yuka MiyataniMinoru Irahara
Apr 18, 2009·Future Cardiology·James P SticeAnne A Knowlton
Sep 4, 2010·Maturitas·Cátia Morgado GameiroCamil Castelo-Branco
Dec 17, 2011·Lancet Neurology·Lynda Lisabeth, Cheryl Bushnell
Aug 10, 2012·Medicine and Science in Sports and Exercise·Melody D PhillipsJoel B Mitchell
Aug 11, 2012·Current Medicinal Chemistry·É ToussirotG Dumoulin
May 28, 2013·Women & Health·Fabiano Henrique Rodrigues Soares, Maria Bernardete Cordeiro de Sousa
Oct 31, 2013·Journal of Women's Health·Sheng Hui WuGong Yang
Dec 21, 2013·Journal of cardiology·Kazuto NakamuraKenneth Walsh
Jan 15, 2014·Best Practice & Research. Clinical Endocrinology & Metabolism·Lionel Hebbard, Barbara Ranscht
Apr 16, 2014·BioMed Research International·Fernando Lizcano, Guillermo Guzmán
Jun 25, 2014·Cardiovascular Diabetology·Enrique Z Fisman, Alexander Tenenbaum
Jun 28, 2014·Climacteric : the Journal of the International Menopause Society·R A LoboR J Baber
Sep 6, 2014·Arteriosclerosis, Thrombosis, and Vascular Biology·Guangyu WuWeiping Jia
Mar 27, 2015·Medicine and Science in Sports and Exercise·Xuewen WangBarbara J Nicklas
Dec 17, 2015·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Vanessa AbellaOreste Gualillo
Oct 7, 2017·Mayo Clinic Proceedings·Ekta KapoorStephanie S Faubion
Jul 11, 2014·Journal of Clinical & Translational Endocrinology·Aline P JarreteAngelina Zanesco
Dec 6, 2017·Menopause : the Journal of the North American Menopause Society·Kristen E GrayAndrea Z LaCroix
Oct 3, 2018·Menopause : the Journal of the North American Menopause Society·Paulo R P NunesFábio L Orsatti
May 24, 2019·Journal of Inflammation Research·Fawaz Y AziziehRaj Raghupathy
Feb 16, 2020·International Journal of Molecular Sciences·Hyung Muk ChoiKyoung Soo Kim

❮ Previous
Next ❯

Citations

Jul 30, 2021·Ageing Research Reviews·Doortje W DekensPetrus J W Naudé

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT01987778

Software Mentioned

Masterplex
xPONENT
SPSS

Related Concepts

Related Feeds

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Biomechanics

Biomechanics examines the generation of internal forces within the body and investigates the effects and control of forces that act on or are produced on tissues. Here are the latest discoveries.