Resistant starch does not affect zinc homeostasis in rural Malawian children

Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)
Thaddaeus MayNancy F Krebs

Abstract

This study tested the hypothesis that Malawian children at risk for zinc deficiency will have reduced endogenous fecal zinc (EFZ) and increased net absorbed zinc (NAZ) following the addition of high amylose maize resistant starch (RS) to their diet. This was a small controlled clinical trial to determine the effects of added dietary RS on zinc homeostasis among 17 stunted children, aged 3-5 years consuming a plant-based diet and at risk for perturbed zinc homeostasis. Dual zinc stable isotope studies were performed before and after 28 d of intervention with RS, so that each child served as their own control. The RS was incorporated into fried wheat flour dough and given under direct observation twice daily for 28 d. Changes in zinc homeostatic measures were compared using paired Student's t-tests and linear regression analysis. Children had a mean height-for-age Z-score of -3.3, and consumed animal source foods ≤twice per month. Their habitual diet contained a phytate:zinc molar ratio of 34:1. Children avidly consumed the RS without complaints. EFZ was 0.8±0.4mg/d (mean±SD) both before and after the intervention. Fractional absorption of zinc was 0.38±0.08 and 0.35±0.06 before and after the RS intervention respectively. NAZ was...Continue Reading

Associated Clinical Trials

References

Mar 1, 1996·The American Journal of Clinical Nutrition·L SianK M Hambidge
Aug 13, 1998·The American Journal of Clinical Nutrition·K M HambidgeL Miller
May 31, 2002·The American Journal of Clinical Nutrition·Mark J ManaryK Michael Hambidge
Feb 1, 1960·Proceedings of the Society for Experimental Biology and Medicine·B L O'DELL, J E SAVAGE
Jul 28, 2004·The American Journal of Clinical Nutrition·Ian J GriffinSteven A Abrams
Sep 10, 2005·European Journal of Nutrition·Lina Yonekura, Hiroo Suzuki
Nov 11, 2005·The American Journal of Clinical Nutrition·Xiao-Yang ShengLeland V Miller
Apr 24, 2007·The Journal of Nutrition·Ananda S Prasad
Apr 27, 2007·The British Journal of Nutrition·Ian J GriffinSteven A Abrams
Jun 23, 2007·The Journal of Nutrition·K Michael HambidgeNancy F Krebs
Nov 9, 2007·Food and Nutrition Bulletin·Bruno de BenoistChristine Hotz
Jan 22, 2008·Lancet·Robert E BlackUNKNOWN Maternal and Child Undernutrition Study Group
Feb 14, 2008·European Journal of Clinical Nutrition·C L Fischer WalkerR E Black
Dec 8, 2011·Plant Biotechnology Journal·Lijia ZhuQiaoquan Liu
Mar 14, 2012·Nutrition Research and Practice·Ae Wha HaWoo Kyoung Kim

❮ Previous
Next ❯

Citations

Oct 21, 2016·European Journal of Clinical Nutrition·M BrnićR Wegmüller
Apr 30, 2019·Journal of Pediatric Gastroenterology and Nutrition·Prasenjit MondalNancy F Krebs

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.