Resolving the Spatial Profile of Figure Enhancement in Human V1 through Population Receptive Field Modeling.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Sonia Poltoratski, Frank Tong

Abstract

The detection and segmentation of meaningful figures from their background is one of the primary functions of vision. While work in nonhuman primates has implicated early visual mechanisms in this figure-ground modulation, neuroimaging in humans has instead largely ascribed the processing of figures and objects to higher stages of the visual hierarchy. Here, we used high-field fMRI at 7 Tesla to measure BOLD responses to task-irrelevant orientation-defined figures in human early visual cortex (N = 6, four females). We used a novel population receptive field mapping-based approach to resolve the spatial profiles of two constituent mechanisms of figure-ground modulation: a local boundary response, and a further enhancement spanning the full extent of the figure region that is driven by global differences in features. Reconstructing the distinct spatial profiles of these effects reveals that figure enhancement modulates responses in human early visual cortex in a manner consistent with a mechanism of automatic, contextually driven feedback from higher visual areas.SIGNIFICANCE STATEMENT A core function of the visual system is to parse complex 2D input into meaningful figures. We do so constantly and seamlessly, both by processing ...Continue Reading

Citations

Nov 18, 2020·Proceedings of the National Academy of Sciences of the United States of America·Ling HuangXilin Zhang
Aug 8, 2021·Nature Communications·Sonia PoltoratskiKalanit Grill-Spector

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