PMID: 8957327Sep 1, 1996Paper

Resorcinols and catechols: a clinical study of cross-sensitivity

American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society
T E KnightA K Prasad

Abstract

All allergic contact dermatitis caused by Philodendron species is common in the Hawaiian islands, and Toxicodendron species are the most common causes of plant-induced allergic contact dermatitis in North America. The purpose of this study was to determine the incidence of cross-sensitivity between these plant species. Alkylresorcinols (pentadec[en]yl and heptadec[en]ylresorcinols) were isolated and purified from extracts of Hawaiian-grown Philodendron scandens subspecies scandens and Philodendron lacerum. Alkylcatechols (mixtures of pentadec[en]ylcatechols from an extract of Toxicodendron radicans (poison ivy) were obtained from the Division of Biologics Standards (National Institutes of Health, Bethesda, MD). Seventeen patients from Hawaii and 8 patients from northern California were skin tested with 5 microL (concentrations, 1 to .001 mg/mL) of each allergen applied to the flexor forearm. The test sites remained open and were graded at 72, 96, and 144 hours. All 8 patients from California were naive to Philodendron species, and 8 patients from Hawaii were naive to Toxicodendron species. No cross-reactivity occurred in patients who were Philodendron sensitive and Toxicodendron naive when tested to the homologous Toxicodendron...Continue Reading

References

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Aug 1, 1962·Archives of Dermatology·H KEIL

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Citations

Apr 4, 1998·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·T K Hamilton, K A Zug
May 8, 2007·Emergency Medicine Clinics of North America·Blake FrobergR Brent Furbee

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