PMID: 4031276Sep 1, 1985Paper

Respiration-dependent ventricular pacing compared with fixed ventricular and atrial-ventricular synchronous pacing: aerobic and hemodynamic variables

Journal of the American College of Cardiology
P RossiM Minella

Abstract

A pacemaker that adapts heart rate in response to the patient's metabolic requirements has been developed. The pacemaker uses breathing frequency and tidal volume as the indicators of physiologic demand. Maximal physical work capacity, anaerobic threshold, oxygen uptake (16 patients) and hemodynamic variables (9 patients) were assessed with fixed rate (VVI), atrial synchronous (VDT/I) and respiration-dependent ventricular (VVI-RD) pacing. All subjects attained their anaerobic threshold in stress tests with VVI pacing. The maximal physical capacity (p less than 0.001), work time to attain the anaerobic threshold (p less than 0.01) and oxygen uptake (p less than 0.001) were significantly greater with VVI-RD than with VVI pacing. The transition from the supine to the standing position was characterized by a significant increase of cardiac index at rest with both VDT/I and VVI-RD pacing as compared with VVI pacing. Progressive increments in the cardiac index and average left ventricular stroke work index were significantly different at submaximal and maximal exercise when VVI and VVI-RD were compared. At maximal exercise, mean cardiac output was also significantly different: 10.21 +/- 2.5 (SD) liters/min with VVI, 11.2 +/- 0.8 lite...Continue Reading

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Citations

Jan 1, 1988·Journal of the American College of Cardiology·P A McElroyK T Weber
Jun 1, 1988·Journal of the American College of Cardiology·T A BuckinghamH L Kennedy
Jan 1, 1990·Pacing and Clinical Electrophysiology : PACE·J D McMeekinS S Gulamhusein
May 1, 1990·Pacing and Clinical Electrophysiology : PACE·R L BateyR C Forney
Jan 1, 1992·Pacing and Clinical Electrophysiology : PACE·M SantomauroM Chiariello
Aug 1, 1992·Pacing and Clinical Electrophysiology : PACE·C P Lau
Aug 1, 1993·Pacing and Clinical Electrophysiology : PACE·N TreeseJ Meyer
Apr 29, 1998·Pacing and Clinical Electrophysiology : PACE·S GarrigueJ Clémenty
Apr 5, 2011·Cardiology Research and Practice·Eraldo OcchettaPaolo Marino
Mar 1, 1991·Progress in Cardiovascular Diseases·M W Baig, E J Perrins
Apr 1, 1989·The American Journal of Cardiology·C P LauA J Camm
Feb 1, 1988·Pacing and Clinical Electrophysiology : PACE·C P LauA J Camm
Sep 1, 1988·Pacing and Clinical Electrophysiology : PACE·P RossiE Occhetta
Oct 1, 1990·Circulation·S Furman
Oct 12, 2000·Pacing and Clinical Electrophysiology : PACE·H IjiriK Tamura
Nov 1, 1986·Pacing and Clinical Electrophysiology : PACE·N E Fearnot, H J Smith
Oct 1, 1990·Pacing and Clinical Electrophysiology : PACE·A FujikiS Sasayama
Jul 1, 1989·Pacing and Clinical Electrophysiology : PACE·L F MoreiraA D Jatene
Nov 1, 1986·Pacing and Clinical Electrophysiology : PACE·T NappholtzT Simmons
Oct 1, 1988·Pacing and Clinical Electrophysiology : PACE·D MehtaA J Camm
Nov 1, 1988·Pacing and Clinical Electrophysiology : PACE·G RognoniP Rossi
Sep 7, 2006·Cardiovascular Engineering·G C BiniG Corbucci

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