PMID: 2501274May 1, 1989Paper

Respiration during exercise in conscious laryngectomized humans

Journal of Applied Physiology
W N Gardner, M S Meah

Abstract

We compared respiratory patterning at rest and during steady cycle exercise at work rates of 30, 60, and 90 W in 7 male chronically laryngectomized subjects and 13 normal controls. Breathing was measured with a pneumotachograph and end-tidal PCO2 by mass spectrometer. Inspired air was humidified and enriched to 35% O2. Peak flow, volume, and times for the inspiratory and expiratory half cycles, time for expiratory flow, minute ventilation, and mean inspiratory flow were computer averaged over at least 40 breaths at rest and during the last 2 min of 5-min periods at each work rate. During the transition from rest to exercise and with increasing work rate in both groups, there was an increase in respiratory rate and depth with selective and progressive shortening of expiratory time; these responses were not significantly different between the two groups, but there was a suggestion that respiratory "drive" as quantitated by mean inspiratory flow may limit in the laryngectomized subjects at high work rates. Time for expiratory flow increased on transition from rest to exercise and then decreased in both groups as the work rate increased; it was shorter in the laryngectomy than control group at all levels. In the laryngectomized sub...Continue Reading

Citations

Dec 1, 1995·Clinical Otolaryngology and Allied Sciences·A H AckerstaffN Van Zandwijk
Jan 1, 2003·Medical & Biological Engineering & Computing·E Magosso, M Ursino
Feb 9, 2002·American Journal of Physiology. Heart and Circulatory Physiology·Elisa MagossoMauro Ursino
Jul 1, 1992·Respiratory Medicine·G F RaffertyW N Gardner

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