Respiration of amniotic fluid in near-term foetal rabbit

European Journal of Obstetrics, Gynecology, and Reproductive Biology
B HaddadD Cabrol

Abstract

To examine the existence of amniotic fluid inhalation in foetal rabbit near term. Rabbit red cells labelled with 51 radio-chromium (Cr51-S1: Injectable solution sodium chromate, volumic activity: 74 MBq/ml; Cis-BioInternational, France) were injected into the amniotic sac of 24 New Zealand White foetal rabbits (mean gestation: 31 days) at day 25 per-laparotomy. At day 26, just prior to caesarean section, human serum albumin labelled with 125 radio-active iode (125I-HSA) (SERALB-125: human serum albumin labelled with radioactive Iode 125, volumic activity: 185 kBq/ml, Cis-BioInternational, France) was injected into each amniotic sac. The lungs, digestive tracts, kidneys and liver were excised separately and radioactivity counted in each organ. On day 26 of gestation, the 51Cr-RC radioactivity rate per gram of tissue in lungs, digestive tract amniotic fluid, liver and kidneys were respectively 1.66 +/- 2.8%, 1.15 +/- 1.6%, 0.015 +/- 0.02% and 0.04 +/- 0.07% of the total amount of radioactivity injected into the amniotic sac at day 25. The lungs' radioactivity was significantly higher than liver (t = 2.94, P < 0.01) or kidneys radioactivity (t = 2.38, P < 0.05). The 125I-HSA injected just prior to caesarean section at day 26 was n...Continue Reading

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Citations

Jun 25, 2010·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Gérard CoureaudBenoist Schaal
Nov 22, 2002·Journal of Perinatal Medicine·Irena Stucin GantarMetka Derganc
Nov 21, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Gilles GrangéDominique Cabrol

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