Oct 22, 1977

Respiratory allergy to urine proteins of rats and mice

Lancet
A N TaylorJ Pepys

Abstract

Five atopic laboratory workers with asthma and other manifestations of allergy to rats and mice were sensitive to low-molecular-weight urine proteins--an alpha2-globulin in the rat and a prealbumin in the mouse. Positive skin prick and inhalation test reactions to the urine proteins were obtained; and radioallergosorbent tests (R.A.S.T.) for specific IgE antibody were also positive. These findings show that proper control of the collection and disposal of the animals' urine is necessary to minimise the likelihood of sensitisation.

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Mentioned in this Paper

Albuminuria
Electrophoresis, Agar Gel
Ttr
Radioallergosorbent Test
Allergens
Occupational Diseases
Asthma
Chemical Fractionation
Hay Fever
Aerosol Dose Form

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