Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.

PloS One
Andreas D FlourisYiannis Koutedakis

Abstract

We assessed the cardiorespiratory and immune response to physical exertion following secondhand smoke (SHS) exposure through a randomized crossover experiment. Data were obtained from 16 (8 women) non-smoking adults during and following a maximal oxygen uptake cycling protocol administered at baseline and at 0-, 1-, and 3- hours following 1-hour of SHS set at bar/restaurant carbon monoxide levels. We found that SHS was associated with a 12% decrease in maximum power output, an 8.2% reduction in maximal oxygen consumption, a 6% increase in perceived exertion, and a 6.7% decrease in time to exhaustion (P<0.05). Moreover, at 0-hours almost all respiratory and immune variables measured were adversely affected (P<0.05). For instance, FEV(1) values at 0-hours dropped by 17.4%, while TNF-α increased by 90.1% (P<0.05). At 3-hours mean values of cotinine, perceived exertion and recovery systolic blood pressure in both sexes, IL4, TNF-α and IFN-γ in men, as well as FEV(1)/FVC, percent predicted FEV(1), respiratory rate, and tidal volume in women remained different compared to baseline (P<0.05). It is concluded that a 1-hour of SHS at bar/restaurant levels adversely affects the cardiorespiratory and immune response to maximal physical exe...Continue Reading

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Citations

Nov 1, 2013·Sports Medicine·Luisa V Giles, Michael S Koehle
Oct 27, 2012·Sports Medicine·Paul T CutrufelloKenneth W Rundell
Jun 28, 2013·International Journal of Environmental Health Research·Andreas D FlourisYiannis Koutedakis
Jun 10, 2016·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Glen P KennyAndreas D Flouris
Jul 29, 2019·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Florence Chau-EtchepareMichael Schivo

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Methods Mentioned

BETA
enzyme-immunosorbent

Software Mentioned

Number Cruncher Statistical Systems
PASW Statistics
PASS
SPSS
PASW

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