Respiratory and intensive care aspects of muscular dystrophies

Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
X AmbrosiD Orlikowski

Abstract

Among the various myopathies, Duchenne muscular dystrophy represents the myopathy with the most stereotypical respiratory evolution. This progressive respiratory failure is going to develop in a parallel way of motor deficit, conducting patients to mechanical ventilation at the end of their second decade. In the absence of curative therapeutics, respiratory cares like home ventilation and prevention of respiratory complications, in a systematic and organized way, allowed to decrease the morbidity and the mortality of these patients. It is not exceptional to meet patients with life expectancy of which overtakes about forty. Besides axial stabilization, cough assistance techniques and swallowing disorders management need to be associated to mechanical ventilation. Invasive techniques of ventilation as tracheostomy keep their place in this pathology even if alternative techniques allowing full day non-invasive ventilation were generalized these last years.

References

Mar 1, 1981·Muscle & Nerve·Y RideauJ Grellet
Feb 1, 1994·Thorax·Y Khan, J Z Heckmatt
Aug 1, 1997·American Journal of Respiratory and Critical Care Medicine·J M PoponickA F DiMarco
Jan 5, 1999·American Journal of Respiratory and Critical Care Medicine·H F BeckerC E Sullivan
Jul 3, 1999·American Journal of Respiratory and Critical Care Medicine·M F PhillipsP M Calverley
Jan 5, 2000·American Journal of Respiratory and Critical Care Medicine·C A Hukins, D R Hillman
Mar 10, 2001·Archives of Physical Medicine and Rehabilitation·C FromageotJ C Raphaël
Dec 26, 2001·American Journal of Respiratory and Critical Care Medicine·M F PhillipsP M Calverley
Aug 21, 2002·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic Society/European Respiratory Society
Feb 5, 2003·Neuromuscular Disorders : NMD·Uwe MelliesHelmut Teschler
Mar 29, 2003·The European Respiratory Journal·M ChatwinA K Simonds
Mar 16, 2005·Respiratory Physiology & Neurobiology·Grégoire TrebbiaFrédéric Lofaso
Mar 31, 2005·Seminars in Neurology·Antonio Culebras
Jun 18, 2005·American Journal of Respiratory and Critical Care Medicine·Malcolm KohlerKonrad E Bloch
Oct 26, 2005·American Journal of Physical Medicine & Rehabilitation·Emilio ServeraJulio Marín
Jul 28, 2006·The European Respiratory Journal·M ToussaintP Soudon
Jun 15, 2007·Seminars in Respiratory and Critical Care Medicine·Anita K Simonds
Aug 21, 2008·Journal of Neurology, Neurosurgery, and Psychiatry·M KohlerK E Bloch
Jun 19, 2010·Neuromuscular Disorders : NMD·Nicolas TerziFrédéric Lofaso
Jul 24, 2013·Annals of Physical and Rehabilitation Medicine·P KienyB Perrouin Verbe
Sep 6, 2014·Revue neurologique·A FayssoilD Orlikowski

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