Respiratory depression after neuraxial opioids in the obstetric setting

Anesthesia and Analgesia
Brendan Carvalho

Abstract

Neuraxial opioids have contributed significantly to improved labor and postcesarean delivery analgesia. In the obstetric population, epidural and intrathecal opioids are associated with a very low risk of clinically significant respiratory depression. Although rare, respiratory depression is a serious risk; patients may die or suffer permanent brain damage as a consequence. This review discusses the mechanism and incidence, as well as the prevention, detection, and management of respiratory depression with morphine, extended-release epidural morphine, and lipophilic opioids in the labor and cesarean delivery setting.

References

May 1, 1992·Anesthesia and Analgesia·S E CohenJ C Levron
Sep 1, 1991·Anesthesiology·L B ReadyL Wild
Sep 1, 1990·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·J G FullerL Palmer
Feb 1, 1990·British Journal of Anaesthesia·M S BrockwayJ H McClure
Mar 1, 1989·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R C EtchesM D Daley
Oct 1, 1988·Anesthesia and Analgesia·B RenaudP Viars
Jan 1, 1986·Canadian Anaesthetists' Society Journal·G H McMorland, M J Douglas
Sep 1, 1984·Anesthesiology·M J Cousins, L E Mather
Dec 1, 1984·British Journal of Anaesthesia·T K AbboudC L Baysinger
Mar 1, 1984·Anesthesia and Analgesia·S C HughesM Norton
Aug 2, 1980·British Medical Journal·P V ScottI M Sumrein
Feb 1, 1981·Anesthesiology·A BarakaS Hajj
Jun 1, 1982·Anesthesiology·P R BromageC H Nielsen
Nov 1, 1995·Anesthesiology·C L Hamilton, S E Cohen
Jul 1, 1995·Anesthesiology·M N Baker, M C Sarna
Aug 1, 1994·Anesthesiology·R L Hays, C M Palmer
Dec 1, 1993·Anesthesia and Analgesia·W M GriecoD Costello
Jun 5, 1998·Regional Anesthesia and Pain Medicine·M C NorrisB Holtmann
Nov 18, 1998·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·S KatsirisS Halpern
May 16, 2002·Anaesthesia·C J Lanigan
Jul 18, 2002·Progress in Lipid Research·Sankaram Mantripragada
Nov 28, 2002·British Journal of Anaesthesia·M CannessonD Chassard
Jun 24, 2003·Anesthesia and Analgesia·Philip E HessStephen D Pratt
Aug 29, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Samuel KoElizabeth G VanDenKerkhof
Jul 1, 1997·International Journal of Obstetric Anesthesia·S C Hughes
Jul 1, 1997·International Journal of Obstetric Anesthesia·J B JaffeeL M Newman
Mar 15, 2005·Regional Anesthesia and Pain Medicine·Stephanie R GoodmanRichard M Smiley
Sep 1, 2005·Anesthesiology·Brenda A BucklinFred A Ullrich

❮ Previous
Next ❯

Citations

Jun 1, 2011·British Journal of Anaesthesia·I Power
Jun 28, 2012·British Journal of Anaesthesia·J HermanidesP Lirk
Jul 28, 2010·Clinical Obstetrics and Gynecology·Scott L Ciarkowski, Caren M Stalburg
Jan 1, 2009·Anesthesiology Research and Practice·Leinani Aiono-Le TagaloaBrendan Carvalho
Aug 21, 2008·Anesthesia and Analgesia·Cynthia A Wong
Mar 29, 2014·International Anesthesiology Clinics·Paul M Wieczorek
Feb 21, 2014·Nigerian Journal of Clinical Practice·A DostbilA Ahiskalioglu
Feb 3, 2016·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Sarah Armstrong, Roshan Fernando
Jan 2, 2013·Annales Françaises D'anesthèsie Et De Rèanimation·H HarkoukD Benhamou
Dec 17, 2009·Best Practice & Research. Clinical Obstetrics & Gynaecology·Robert A DyerMichael F James
Mar 31, 2010·Journal of Clinical Pharmacology·Mark S MorrisSteven E Domino
Nov 9, 2011·Journal of Midwifery & Women's Health·Judith P Rooks
Jul 22, 2014·Journal of Veterinary Emergency and Critical Care·Miguel MartínezJo Murrell
Sep 27, 2016·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·Lois OswaldJoyanne Pfeffer
Jul 13, 2016·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Robert Bolash
Oct 22, 2016·Acta Anaesthesiologica Scandinavica·H LiuA D Kaye
Nov 22, 2016·Anesthesia and Analgesia·Carolyn F WeinigerSharon Einav
Jan 14, 2017·Regional Anesthesia and Pain Medicine·Ki Jinn ChinJeffrey Gadsden
Jun 15, 2017·Anesthesia and Analgesia·Brendan Carvalho, Carolyn F Weiniger
Mar 22, 2018·Anesthesiology·Grace LimHolger K Eltzschig
Nov 22, 2014·Journal of Occupational and Environmental Medicine·Kurt T HegmannUNKNOWN American College of Occupational and Environmental Medicine
Mar 27, 2015·Anesthesia and Analgesia·Lisa Leffert
Aug 30, 2017·Scandinavian Journal of Pain·Hadeel Al-KazwiniLeiv Arne Rosseland
Oct 3, 2020·Case Reports in Obstetrics and Gynecology·Leila MagistradoKjersti M Aagaard
Apr 13, 2021·International Anesthesiology Clinics·Hon Sen TanAshraf S Habib
Jun 30, 2021·Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS·Julia Oji-ZurmeyerStefan Jochberger

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.