PMID: 16528903Mar 15, 2006Paper

Respiratory development of 5- to 6- year-old children experiencing a first bronchiolitis episode before age one

European Annals of Allergy and Clinical Immunology
M SznajderGeneral Pediatrics Group of the French Society of Pediatrics

Abstract

The relationship between early infections due to respiratory syncytial virus (RSV), particularly bronchiolitis in infancy, and the subsequent development of asthma, bronchial hyper-responsiveness, and/or other allergic manifestations, seems increasingly certain, even if the mechanisms involved are not yet quite clear. The objectives of this work were to determine the prevalence of, and risk factors for, asthma and allergy in 5 to 6 year-old children who five years previously, had experienced their first episode of bronchiolitis before the age of twelve months, and to define the possible effect of the age at which the bronchiolitis occurred on the subsequent development of asthma. A retrospective cohort survey was conducted, based on the registers of two hospital paediatric emergency units (Unit A: the Ambroise Pare teaching hospital at Boulogne, France and unit B: the General Hospital of Cherbourg, France). The cohort comprised 5-6 years old children who had consulted or been admitted to emergency unit A or B between October 1993 and March 1994 for a first attack of bronchiolitis before the age of 12 months. One hundred and twenty eight children were included in the two centres (centre A: 78; centre B: 50). A familial history o...Continue Reading

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