Respiratory infections associated with nontuberculous mycobacteria in non-HIV patients

The European Respiratory Journal
M DaillouxFrench Mycobacteria Study Group


The incidence of nontuberculous mycobacteria (NTM) pulmonary diseases in HIV-negative patients was studied prospectively from January 1, 2001 to December 31, 2003 by 32 sentinel sites distributed throughout France. In total, 262 patients who yielded NTM isolates from respiratory clinical specimens, met the bacteriological, radiological and clinical criteria established by the American Thoracic Society for NTM respiratory disease. Among the 262 NTM isolates, 234 were slow-growing mycobacteria (125 Mycobacterium avium-intracellulare complex (MAC), 66 M. xenopi, 34 M. kansasii) and 28 were rapidly growing mycobacteria (25 M. abscessus complex). In the Paris area, M. xenopi was the most frequently isolated species, followed by MAC. Most patients (>50%), except those with M. kansasii, had underlying predisposing factors such as pre-existing pulmonary disease or immune deficiency. Asthenia, weight loss, chronic cough and dyspnoea were the most common clinical symptoms. The classical radiological appearance of NTM infections was indistinguishable from that observed in patients with pulmonary tuberculosis. In summary, the incidence of nontuberculous mycobacteria pulmonary infections in HIV-negative patients was estimated at 0.74, 0.73 ...Continue Reading

Associated Clinical Trials


Apr 10, 2010·Lung·Emmet E McGrathPaul B Anderson
Feb 17, 2009·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·H Grubek-JaworskaR Chazan
May 17, 2008·Journal of Veterinary Internal Medicine·C MeeksS G Hirsch
Oct 23, 2009·Journal of Clinical Microbiology·Anne-Laure RouxUNKNOWN Jean-Louis Herrmann for the OMA Group
Nov 11, 2008·Canadian Journal of Microbiology·Helena SebakovaJaroslav Sasek
Dec 17, 2009·American Journal of Respiratory and Critical Care Medicine·Claire AndréjakReimar W Thomsen
Apr 29, 2008·American Journal of Respiratory Cell and Molecular Biology·Elizabeth P SampaioSteven M Holland
Mar 31, 2010·BMC Microbiology·Frédéric-Antoine DauchyJeanne Maugein
Nov 2, 2011·Internal Medicine·Satoshi IkegameAkira Kajiki
Dec 14, 2011·Revue des maladies respiratoires·C AndréjakV Jounieaux
Mar 30, 2007·Der Internist·B KhanlariM Battegay
Jan 12, 2008·Chest·Jeffrey Glassroth
Dec 3, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Yu-Jung TungYen-Hsu Chen
Nov 29, 2011·Revista clínica española·E Martínez-CerónR Álvarez-Sala
Aug 3, 2010·Infectious Disease Clinics of North America·Babafemi Taiwo, Jeff Glassroth
Sep 8, 2009·Diagnostic Microbiology and Infectious Disease·Pierre AbgueguenEric Pichard
Nov 18, 2008·European Journal of Internal Medicine·Emmet E McGrath, Philip Bardsley
Nov 13, 2007·Respiratory Medicine·Sunghoon ParkWon-Jung Koh
Mar 19, 2014·International Journal of Medical Microbiology : IJMM·Rachel ThomsonMegan Hargreaves
Oct 20, 2012·Scandinavian Journal of Infectious Diseases·Bethany S DaviesHeather J Milburn
Jul 17, 2010·Scandinavian Journal of Infectious Diseases·António AmorimEdna Pereira
Aug 19, 2014·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Xiuqin ZhaoYu Pang
Dec 15, 2015·International Journal of Mycobacteriology·Ali Akbar VelayatiMehdi Mirsaeidi
May 27, 2009·Respiratory Medicine·Chun-Ta HuangUNKNOWN Tami Group
Jul 7, 2009·Respiratory Medicine·Hee-Jung JunWon-Jung Koh
Feb 14, 2015·Clinics in Chest Medicine·D Rebecca Prevots, Theodore K Marras
Oct 3, 2014·Journal of Clinical Microbiology·Aurélie RenvoiséJérôme Robert
Feb 25, 2018·Infection·Tatjana Adzic-VukicevicSalvatore Rubino
Nov 26, 2009·Expert Opinion on Pharmacotherapy·Jaime Esteban, Alberto Ortiz-Pérez
Oct 10, 2013·Annals of the American Thoracic Society·Kozo MorimotoShoji Kudoh
Aug 19, 2014·The Clinical Respiratory Journal·Abdullah Al-HarbiMohammad Khan
Oct 20, 2019·International Journal of Environmental Research and Public Health·Helena ModráIvo Pavlík

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