PMID: 9527149Apr 4, 1998Paper

Respiratory insufficiency due to high anterior cervical cord infarction

Journal of Neurology, Neurosurgery, and Psychiatry
R S HowardA J Williams

Abstract

Respiratory dysfunction may occur as a result of lesions in the upper cervical spinal cord disturbing the descending pathways subserving automatic and volitional ventilatory control. Four patients are described who presented with acute respiratory insufficiency caused by infarction of the anterior portion of the upper cervical cord due to presumed anterior spinal artery occlusion. Two patients presented after respiratory arrests; they were ventilated and there was no automatic or volitional respiratory effort. Both had signs of an extensive anterior spinal cord lesion at the C2 level and this was confirmed by MRI. One patient presented with a C4 infarction and required ventilation for three months. Ventilatory recovery was characterised by the development of an automatic respiratory pattern. The fourth patient required ventilation for two months after infarction at the C3 level. On attempted weaning he had prolonged periods of hypoventilation and apnoea during inattention and sleep indicating impairment of automatic respiratory control. Infarction of the spinal cord at high cervical levels may be due to fibrocartilaginous embolism and involvement of the descending respiratory pathways may occur. Extensive lesions at C1/2 cause ...Continue Reading

References

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Citations

Oct 26, 2001·Postgraduate Medical Journal·R S HowardA J Williams
Feb 5, 2009·Clinical & Developmental Immunology·Jorge Schettini, Pinku Mukherjee
Jul 31, 2010·Journal of Oncology·Claudia PapewalisMatthias Schott
Sep 23, 2003·Anesthesia and Analgesia·Susumu FujiokaShigeho Morita
Oct 3, 2009·Internal Medicine·Hideyuki MatsumotoIchiro Imafuku
Sep 7, 2004·Journal of Neurosurgery. Spine·Hiromitsu ToyodaKunio Takaoka
Jun 26, 2013·Respiratory Physiology & Neurobiology·David D FullerNicole J Tester
Feb 25, 2009·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·M MachnowskaS Wiebe
Sep 10, 2011·AJNR. American Journal of Neuroradiology·J E Walden, M Castillo
May 17, 2014·The International Journal of Neuroscience·Maurilio GenoveseGiuliana Galassi
Mar 3, 2017·Annals of Neurology·Eelco F M Wijdicks
Aug 20, 2002·The Annals of Otology, Rhinology, and Laryngology·Koichi OmoriMasaru Yamashita
Jul 4, 2012·Journal of Child Neurology·Neil R Holland
Jan 6, 2017·Spinal Cord Series and Cases·Atsushi TanidaHideki Nagashima
Mar 30, 2021·Revue neurologique·D Leys, J-P Pruvo

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