Respiratory muscle strength in relation to sarcopenia in elderly cardiac patients

Aging Clinical and Experimental Research
Kazuhiro P IzawaYoshihiro J Akashi

Abstract

Little information exists on the relation between respiratory muscle strength such as maximum inspiratory muscle pressure (MIP) and sarcopenia in elderly cardiac patients. The present study aimed to determine the differences in MIP, and cutoff values for MIP according to sarcopenia in elderly cardiac patients. We enrolled 63 consecutive elderly male patients aged ≥65 years with cardiac disease in this cross-sectional study. Sarcopenia was defined based on the European Working Group on Sarcopenia in Older People algorithm, and, accordingly, the patients were divided into two groups: the sarcopenia group (n = 24) and non-sarcopenia group (n = 39). The prevalence of sarcopenia in cardiac patients and MIP in the patients with and without sarcopenia were assessed to determine cutoff values of MIP. After adjustment for body mass index, the MIP in the sarcopenia group was significantly lower than that in the non-sarcopenia group (54.7 ± 36.8 cmH2O; 95 % CI 42.5-72.6 vs. 80.7 ± 34.7 cmH2O; 95 % CI 69.5-92.0; F = 4.89, p = 0.029). A receiver-operating characteristic curve analysis of patients with and without sarcopenia identified a cutoff value for MIP of 55.6 cmH2O, with a sensitivity of 0.76, 1-specificity of 0.37, and AUC of 0.70 (9...Continue Reading

References

May 8, 2003·Intensive Care Medicine·Joachim E FischerRoman Jaeschke
May 29, 2009·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Lutz FrankensteinChristian Zugck
Apr 16, 2010·Age and Ageing·Alfonso J Cruz-JentoftUNKNOWN European Working Group on Sarcopenia in Older People
Nov 16, 2010·Current Opinion in Clinical Nutrition and Metabolic Care·Yves RollandBruno Vellas
May 31, 2011·Respiratory Medicine·Meral Bosnak-GucluLale Tokgözoglu
Dec 20, 2011·Heart & Lung : the Journal of Critical Care·Laura Maria Tomazi NevesAparecida Maria Catai
Sep 4, 2012·The Journal of Thoracic and Cardiovascular Surgery·Metka KodricMarco Confalonieri
Mar 14, 2013·Current Opinion in Clinical Nutrition and Metabolic Care·Hiroshi Kaji
May 2, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Jwa-Kyung KimYoung Rim Song
Sep 21, 2013·Current Pharmaceutical Design·Giuseppe LippiMartina Montagnana
Mar 13, 2014·Geriatrics & Gerontology International·Kazuhiro P IzawaKoichiro Oka

❮ Previous
Next ❯

Citations

Aug 10, 2016·International Journal of Cardiology·Kazuhiro P IzawaYoshihiro J Akashi
Oct 18, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·Sarah J PetersonSharon Foley
Aug 28, 2020·Journal of Clinical Medicine·Francisco Miguel Martínez-ArnauOmar Cauli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.