PMID: 9451574Feb 6, 1998Paper

Respiratory sinus arrhythmia during anaesthesia: assessment of respiration related beat-to-beat heart rate variability analysis methods

International Journal of Clinical Monitoring and Computing
P LoulaA Yli-Hankala

Abstract

Beat-to-beat heart rate variability analysis is a powerful tool for the diagnosis of neuropathy. Respiration-related heart rate variability (respiratory sinus arrhythmia, RSA) reflects the function of parasympathetic nervous system during spontaneous ventilation while awake. RSA is also claimed to monitor the depth of anaesthesia. Power spectrum analysis or various averaging techniques of the heart rate variability are usually applied. The current literature, however, does not usually interpret the ground rules and limitations of the method used, and this may sometimes lead to erroneous conclusions on the data. The aim of our study was to compare and analyse critically the performance of different methods of evaluating RSA during anaesthesia and positive pressure ventilation. Power spectrum analysis, the root mean square of the successive RR-interval difference (RMSSD), and two respiration related methods, RSA index and average phase RSA, were included in the comparison. To test these methods, 11 patients were anaesthetised with isoflurane and their lungs were ventilated mechanically with a frequency of 6 cycles min-1. Each patient received a bolus dose of atropine (20 micrograms kg-1) during the trial. Electrocardiogram, elect...Continue Reading

References

Aug 1, 1992·Journal of Cardiovascular Pharmacology·P O Julu
Jan 1, 1992·Experimental Physiology·P KohlT Streubel
Apr 1, 1992·British Journal of Anaesthesia·D C GalletlyB J Robinson
Mar 1, 1991·Acta Physiologica Scandinavica·A Yli-HankalaV Jäntti
May 1, 1981·Psychophysiology·J R JenningsG Turpin
Aug 1, 1993·British Journal of Anaesthesia·C J PomfrettT E Healy
Jan 1, 1994·Journal of Clinical Monitoring·R S Jaffe, D L Fung
Nov 1, 1993·British Journal of Anaesthesia·P AnnilaL Lindgren
Sep 1, 1993·British Journal of Anaesthesia·D Y WangT E Healy
May 1, 1964·Journal of Applied Physiology·A ANGELONE, N A COULTER

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