PMID: 2506967Aug 5, 1989Paper

Respiratory symptoms as predictors of 27 year mortality in a representative sample of British adults

BMJ : British Medical Journal
L CarpenterH Inskip

Abstract

To examine associations between reported respiratory symptoms (as elicited by questionnaire) and subsequent mortality. Prospective cohort study. 92 General practices in Great Britain. A nationally representative sample of 1532 British men and women aged between 40 and 64. Mortality from all causes, cardiovascular disease, lung cancer, and chronic bronchitis. Subjects were interviewed in 1958 regarding various respiratory symptoms (including cough, phlegm, breathlessness, and wheeze) by using a questionnaire which formed the basis of the Medical Research Council's questionnaire on respiratory symptoms. By the end of 1985, 889 deaths had been reported, including 51 in men due to chronic bronchitis. After adjustment for differences in age and smoking habits death rates from chronic bronchitis in men who reported symptoms were greater than those in men who did not for each of the symptoms examined. The adjusted mortality ratios were 3.4 (95% confidence interval 1.8 to 6.5) for morning cough, 3.7 (2.0 to 6.9) for morning phlegm, 6.4 (3.0 to 13.8) for breathlessness when walking on the level, and 10.5 (4.4 to 24.6) for wheeze most days or nights. Mortality ratios were also significantly raised for four episodic symptoms not usually i...Continue Reading

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Citations

Sep 8, 2011·Journal of Palliative Medicine·Arif H KamalAmy P Abernethy
Dec 1, 1989·Archives of Disease in Childhood·J A Davis
Nov 15, 2000·Journal of Epidemiology and Community Health·A LanghammerL Bjermer
Dec 13, 2006·BMC Health Services Research·Alison M ElliottKate Hunt
Nov 11, 2010·Journal of Occupational and Environmental Medicine·Luenda E CharlesHeather M Ochs-Balcom
Dec 1, 1994·The American Journal of the Medical Sciences·B BarkleyH P Hazuda
May 12, 2009·Respiratory Physiology & Neurobiology·Claudine Peiffer
Dec 3, 2014·Autoimmunity Reviews·Tomer BashiYehuda Shoenfeld
Jul 4, 2019·Respirology : Official Journal of the Asian Pacific Society of Respirology·Kate PetrieJohnson George
May 12, 2020·Frontiers in Immunology·Diego G PeroniPasquale Comberiati
May 29, 2021·JAMA Internal Medicine·Adam W GaffneySteffie Woolhandler
Dec 17, 2021·Asthma Research and Practice·Martina Yaneva, Razvigor Darlenski

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