PMID: 11323792Apr 27, 2001Paper

Respiratory symptoms, lung function and cell surface markers in a group of hemp fiber processors

American Journal of Industrial Medicine
D FishwickA D Curran

Abstract

Hemp dust exposure is associated with byssinosis and accelerated lung loss in longitudinal studies. The immunological changes associated with hemp dust exposure are less well understood. We studied a small group of current male hemp processors with a mean age of 43 years. Questionnaire data, lung function, serial FEV(1) and blood were collected from all workers. In total, seven workers (64%) complained of at least one respiratory symptom (one with byssinosis). The mean percentage predicted FEV(1) was 91.5, FVC 97.7, PEF 92.1, and FEF(25-75) 79.5. Serial FEV(1) measurements in the two workers with work-related respiratory symptoms revealed a mean change in FEV(1) on the first working day of -12.9%. This contrasted with +6.25% on the last working day. Respective values for the two workers without work-related symptoms were -1.4 and +3.2%. Lung function changes and abnormalities in a profile of cell surface activation markers and antibodies were noted to relate to the presence of work-related respiratory symptoms, not seen in the control group.

References

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May 1, 1992·The American Review of Respiratory Disease·D FishwickE B Faragher
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Jan 1, 1998·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals· Jillian R M Swan Andrew D Curran Paul N Beckett

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Citations

Jan 17, 2008·Respirology : Official Journal of the Asian Pacific Society of Respirology·Su W HiiMatthew T Naughton
Jan 26, 2018·Journal of Occupational and Environmental Hygiene·Brett J GreenDonald H Beezhold
Oct 4, 2018·International Journal of Occupational and Environmental Health·Maggie DavidsonGary Dennis
Jul 25, 2019·American Journal of Industrial Medicine·James R CouchDonald H Beezhold
Feb 14, 2020·Annals of Work Exposures and Health·James R CouchMark M Methner
Jul 23, 2020·Annals of Work Exposures and Health·Brynne SilveyChristopher D Simpson
Jul 2, 2020·Annals of Work Exposures and Health·Melinda GardnerMaggie Davidson

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