Respiratory syncytial virus detection by Remel Xpect, Binax Now RSV, direct immunofluorescent staining, and tissue culture

Journal of Clinical Microbiology
Anita P BorekAlexandra Valsamakis

Abstract

The performance characteristics of Xpect RSV (XP) and Binax Now RSV (BN) were compared to those of direct fluorescent-antibody staining and/or tissue culture for detection of respiratory syncytial virus (RSV) in nasopharyngeal aspirate and wash samples from children (n = 110) and adults (n = 66). The sensitivity, specificity, positive predictive value, and negative predictive value of XP were 75%, 98%, 95%, and 90%, respectively; and those of BN were 74%, 100%, 100%, and 90%, respectively. The performances of the assays were similar within a given age group and specimen type (nasopharyngeal aspirate or wash specimen). XP and BN are useful for screening for RSV in respiratory specimens when large volumes are tested or low levels of staffing occur.

References

Jul 10, 2004·Journal of Clinical Microbiology·Marilyn J Ohm-SmithBarbara L Haller
Aug 18, 2004·Diagnostic Microbiology and Infectious Disease·Wade K AldousJudy A Daly
Sep 15, 2004·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Xiaotian ZhengBen Z Katz
Apr 29, 2005·The New England Journal of Medicine·Ann R FalseyEdward E Walsh

❮ Previous
Next ❯

Citations

Apr 17, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David R MurdochUNKNOWN PERCH Core Team
Jan 3, 2008·The Pediatric Infectious Disease Journal·Kelly J Henrickson, Caroline Breese Hall
Apr 23, 2008·Current Opinion in Pulmonary Medicine·Yoshihiko Murata
Jan 16, 2007·Clinical Microbiology Reviews·Diane S Leland, Christine C Ginocchio
Oct 16, 2008·Clinical Microbiology Reviews·James B Mahony
May 14, 2010·Journal of Clinical Microbiology·Christine C GinocchioBelinda Yen-Lieberman
Sep 30, 2010·Immunotherapy·Lawrence M KauvarRalph A Tripp
Jan 3, 2014·Advances in Virology·Swapnil Subhash BawageShree Ram Singh
Feb 19, 2013·Diagnostic Microbiology and Infectious Disease·Dana HawkinsonRebecca Horvat
Aug 3, 2010·Infectious Disease Clinics of North America·David R MurdochTrevor P Anderson
Oct 24, 2013·Journal of Medical Virology·Roberto S GómezAlexis M Kalergis
Jun 30, 2014·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Jeremiah BellRangaraj Selvarangan
Mar 19, 2016·Journal of Medical Virology·Bo Kyeung JungChae Seung Lim
Apr 9, 2017·Current Allergy and Asthma Reports·Kai Sen TanDe-Yun Wang
Jul 19, 2014·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·J Jeremiah BellRangaraj Selvarangan
Apr 23, 2008·Current Opinion in Pulmonary Medicine·Patrick G P Charles
Dec 22, 2011·Critical Reviews in Clinical Laboratory Sciences·James B MahonyMarek Smieja
Jan 1, 2012·Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics·Hidehisa Kohno
Jan 17, 2020·Journal of Medical Virology·Naru ZhangShibo Jiang
Apr 23, 2008·Current Opinion in Pulmonary Medicine

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.