May 30, 1998

Respiratory syncytial virus infection in infants hospitalized with respiratory illness in northern Jordan

Journal of Tropical Pediatrics
M M MeqdamN Abuharfeil

Abstract

During the winter seasons of 1993 and 1994, a total of 256 nasopharyngeal aspirates (NPA) from infants aged less than 1 year old admitted to the pediatric ward of Princess Rahma Hospital, northern Jordan, with bronchiolitis and/or pneumonia, were tested for the presence of respiratory syncytial virus (RSV) using direct immunofluorescence assay (DFA) and cell culture (CC). Of the 256 specimens, 129 (50 per cent) were found positive by both DFA and CC, whereas 24 specimens (9 per cent) and 16 specimens (6 per cent) were found positive by DFA and CC, respectively. In an evaluation of the collected NPA specimens detected by DFA, a sensitivity of 89 per cent and a specificity of 78 per cent were demonstrated. These data suggest that virus isolation in CC is still important for the diagnosis of RSV, although DFA is a valuable, rapid diagnostic assay.

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Mentioned in this Paper

Respiratory Syncytial Virus Infections
Nasopharynx
Bronchiolitis
Hospitalization
Cell Culture Techniques
Seasonal Variation
Aspirate Substance
Direct Immunofluorescence
Upper Respiratory Infections
Respiratory syncytial virus

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