Respiratory syncytial virus outbreak in a tertiary hospital Neonatal Intensive Care Unit

Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)
Carlos Moreno ParejoManuel Conde Herrera

Abstract

Investigation and control of a respiratory syncytial virus (RSV) outbreak that affected the Neonatal Intensive Care Unit (NICU) of a university hospital from October to December 2012. Cohort study of children admitted to the NICU. The infection attack rate was calculated. A descriptive analysis of the cases and a multivariate analysis was performed using the variables that were shown to be risk factors for RSV infection. Preventive measures taken were: contact isolation; hand hygiene training and observation; exclusivity of a health team of nurses and physicians for positive cases, restrictions on visitor numbers; surveillance RSV testing, and palivizumab prophylaxis. The outbreak had three epidemic waves and 20 positive cases out of a total of 48 children admitted. The overall attack rate was 42%. Half of positive cases were children, with a median age of 36 days (p25=22, p75=58). The independent risk factors for RSV infection were birth weight below 1000 grams (OR=23.5; P=.002) and to have another nosocomial infection the week before the diagnosis of RSV infection (OR=19.98; P=.016). It was an outbreak with a high number of cases, due to the delay in notification, prolonged RSV carrier status, and low adherence to hand hygien...Continue Reading

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Citations

Jun 6, 2017·Current Opinion in Infectious Diseases·Julia Johnson, Caroline Quach
Apr 7, 2020·Journal of the Pediatric Infectious Diseases Society·Erica Billig RoseGayle E Langley

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