Response of Freshwater Biofilms to Antibiotic Florfenicol and Ofloxacin Stress: Role of Extracellular Polymeric Substances

International Journal of Environmental Research and Public Health
Chaoqian WangZhiyong Guo

Abstract

Antibiotic residues have been detected in aquatic environments worldwide. Biofilms are one of the most successful life forms, and as a result are ubiquitous in natural waters. However, the response mechanism of freshwater biofilms to the stress of various antibiotic residues is still unclear. Here, the stress of veterinary antibiotic florfenicol (FF) and fluoroquinolone antibiotic ofloxacin (OFL) on freshwater biofilms were investigated by determining the changes in the key physicochemical and biological properties of the biofilms. The results showed that the chlorophyll a content in biofilms firstly decreased to 46⁻71% and then recovered to original content under the stress of FF and OFL with high, mid, and low concentrations. Meanwhile, the activities of antioxidant enzymes, including superoxide dismutase and catalase, increased between 1.3⁻6.7 times their initial values. FF was more toxic to the biofilms than OFL. The distribution coefficients of FF and OFL binding in extracellular polymeric substances (EPS)-free biofilms were 3.2 and 6.5 times higher than those in intact biofilms, respectively. It indicated that EPS could inhibit the FF and OFL accumulation in biofilm cells. The present study shows that the EPS matrix, as t...Continue Reading

References

Jul 9, 1999·Archives of Biochemistry and Biophysics·S DukanD Touati
Nov 10, 2001·Trends in Biochemical Sciences·A W Rutherford, A Krieger-Liszkay
Jul 5, 2005·The Science of the Total Environment·Marina IsidoriAlfredo Parrella
Jan 17, 2007·Analytical and Bioanalytical Chemistry·Sergi SabaterMechthild Schmitt-Jansen
Aug 21, 2010·Environmental Toxicology·Haifeng QianZhengwei Fu
Sep 21, 2010·Current Opinion in Microbiology·Gerard D Wright
Sep 29, 2012·Ecotoxicology and Environmental Safety·Ying LiuQinyan Yue
Feb 6, 2013·Environmental Toxicology and Pharmacology·Wanwan YangLirong Song
Mar 5, 2013·International Journal of Medical Microbiology : IJMM·Frida MarianaThomas Maskow
Sep 6, 2014·Current Pharmaceutical Design·Claire MartinKen M A Kenward
Feb 17, 2015·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ruixin GuoJianqiu Chen
Sep 19, 2015·Environmental Science and Pollution Research International·Jianxing WangYuansong Wei
Aug 12, 2016·Nature Reviews. Microbiology·Hans-Curt FlemmingStaffan Kjelleberg
Dec 31, 2017·The Science of the Total Environment·Liwen ZhangZhiyong Guo
Jan 13, 2018·Water Research·Bruce E Rittmann
Jun 28, 2018·Environmental Science and Pollution Research International·Sinan HeZhiyong Guo
Oct 8, 2018·The Science of the Total Environment·Lingzhan MiaoTengfei Li

❮ Previous
Next ❯

Citations

Apr 24, 2020·International Journal of Occupational Safety and Ergonomics : JOSE·Jianhao WangMingwei Yan
Aug 29, 2020·Journal of Fish Diseases·Andrew P DesboisElizabeth Buba
Feb 8, 2020·International Journal of Environmental Research and Public Health·Wei ZhongJianhui Song

❮ Previous
Next ❯

Methods Mentioned

BETA
environmental stress
infrared spectroscopy

Software Mentioned

SPSS
Origin

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.