Response of Membranes and Vesicles to Capillary Forces Arising from Aqueous Two-Phase Systems and Water-in-Water Droplets

The Journal of Physical Chemistry. B
Reinhard Lipowsky

Abstract

Aqueous two-phase systems and water-in-water emulsions have attracted much recent interest. Here, we theoretically study the interactions of such systems with biomimetic membranes and giant unilamellar vesicles (GUVs). For partial wetting, the water-water interface and the membrane form a three-phase contact line that partitions the membrane into two distinct segments with different tensions and different curvature-elastic properties. On the nanometer scale, the capillary forces arising from the water-water interface lead to a smoothly curved membrane that forms an intrinsic contact angle with the interface. The corresponding balance conditions are derived here for general curvature-elastic parameters of the two membrane segments. On the micrometer scale, the capillary forces deform the membrane segments into spherical caps with an apparent kink along the contact line. A new computational method is introduced by which these piece-wise spherical vesicle shapes can be analyzed in a systematic manner. The method is based on a general relationship that is reminiscent of Neumann's triangle but depends explicitly on the curvatures of the membrane segments. For certain regions of the parameter space, corresponding to small or large sp...Continue Reading

References

Nov 1, 1973·Zeitschrift Für Naturforschung. Teil C: Biochemie, Biophysik, Biologie, Virologie·W Helfrich
Jun 1, 1994·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·L MiaoH G Döbereiner
Mar 1, 1996·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·F Jülicher, R Lipowsky
Jun 27, 2000·Biophysical Journal·W RawiczE Evans
Nov 7, 2002·Journal of the American Chemical Society·Marcus R HelfrichChristine D Keating
Mar 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·M Scott LongChristine D Keating
Dec 21, 2007·Journal of the American Chemical Society·M Scott LongChristine D Keating
Aug 21, 2008·Journal of the American Chemical Society·Yanhong LiRumiana Dimova
Apr 7, 2010·Physical Review Letters·Halim KusumaatmajaReinhard Lipowsky
Mar 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Yanhong LiRumiana Dimova
Jan 17, 2012·The Journal of Physical Chemistry. B·Yanhong LiRumiana Dimova
Feb 2, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Yonggang LiuRumiana Dimova
Mar 8, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Gireeshkumar BalakrishnanDominique Durand
Jun 14, 2012·Chemical Society Reviews·Mara G FreireLuís Paulo N Rebelo
Feb 6, 2013·Lab on a Chip·Jonathan B BoreykoC Patrick Collier
Mar 19, 2014·Advances in Colloid and Interface Science·Reinhard Lipowsky
Jul 30, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Ehsan AtefiHossein Tavana
Jul 28, 2015·Biotechnology Journal·Ruben R G SoaresM Raquel Aires-Barros
Jan 13, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Rilton Alves de FreitasLazhar Benyahia
May 21, 2016·Cell·Louis-Philippe Bergeron-SandovalStephen W Michnick

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Citations

May 1, 2019·Chembiochem : a European Journal of Chemical Biology·Nicolas Martin
Nov 22, 2019·Chemical Society Reviews·Youchuang Chao, Ho Cheung Shum
Oct 8, 2021·Soft Matter·Eriko ShinoharaMiho Yanagisawa

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