PMID: 6410897Aug 1, 1983Paper

Response of patients with irritable bowel syndrome and lactase deficiency using unfermented acidophilus milk

The American Journal of Clinical Nutrition
A D NewcomerD B McGill

Abstract

Acidophilus milk has been reported to help patients with irritable bowel syndrome by correcting the "imbalance of flora" and to be tolerated better by lactase-deficient subjects by providing bacterial lactase in the small intestine. In a double-blind randomized study, 61 lactase-sufficient patients with irritable bowel syndrome each ingested 240 ml of milk three times a day for 2 wk and the same amount of acidophilus milk for an additional 2 wk. The degree of symptoms during the two milk-drinking periods was the same as during the control periods. Also, 18 lactase-deficient patients ingested unaltered milk for 1 wk and acidophilus milk for 1 additional wk. There was no difference in the degree of tolerance to the two varieties of milk. In summary, patients with irritable bowel syndrome were not helped by the ingestion of acidophilus milk, and lactase-deficient patients were as intolerant to acidophilus milk as to unaltered milk.

Citations

Oct 1, 1989·Journal of Dairy Science·S E Gilliland
Jan 5, 1984·The New England Journal of Medicine·A D Newcomer, D B McGill
Jan 1, 1994·Scandinavian Journal of Gastroenterology. Supplement·A Tamm
Mar 10, 2001·Journal of Dairy Science·M E Sanders, T R Klaenhammer
May 2, 2013·Journal of Clinical Gastroenterology·Michael LevittAasma Shaukat
Feb 1, 1987·Journal of Dairy Science·D A Savaiano, M D Levitt
Jan 1, 1991·Scandinavian Journal of Gastroenterology. Supplement·H A BüllerR J Grand
Sep 1, 1990·FEMS Microbiology Reviews·S E Gilliland
Mar 31, 2005·Journal of Clinical Gastroenterology·Martin H Floch
May 1, 1991·Journal of Dairy Science·N Shah, P Jelen
Jan 1, 2012·Microbial Ecology in Health and Disease·Riitta Korpela, Leena Niittynen

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