Response preparation in Parkinson's disease: automatic vs. controlled processing

Acta Psychologica
J J AdamPaloma Marí-Beffa

Abstract

Using a finger cuing paradigm, we investigated response preparation in Parkinson's disease (PD). The central question was whether PD individuals are differentially affected by preparatory cues that specify a more automatic response set configuration (that induces within-hand preparation) as opposed to a more controlled one (that induces between-hands preparation). Reaction times (RTs) and error rates were measured in 20 non-demented individuals with PD and 20 healthy control participants with a long and short preparation interval (500 ms and 2000 ms). RT benefits and/or costs were measured for cues indicating a within- and between-hands motor preparatory set. Overall, RTs were significantly longer, and errors more frequent, for PD participants than for control participants. More importantly, in comparison with control subjects, PD individuals showed a significant deficit in between-hands preparation but not in within-hand preparation. Furthermore, longer preparation intervals slowed down cued RTs of the control participants, but not those of the PD individuals. Together, these findings suggest that whereas automatic response preparation processes are spared in PD, controlled response preparation processes operate at a slower ra...Continue Reading

References

Jul 1, 1990·Trends in Neurosciences·G E Alexander, M D Crutcher
Feb 1, 1980·The Quarterly Journal of Experimental Psychology·M I Posner
Feb 5, 2000·Neuropsychologia·L JänckeH Steinmetz
Feb 27, 2001·Journal of Cognitive Neuroscience·P Praamstra, F M Plat
Oct 24, 2001·Brain : a Journal of Neurology·A BerardelliM Hallett
Jan 10, 2002·Journal of Clinical and Experimental Neuropsychology·W L ArnottP A Silburn
May 7, 2002·Journal of Clinical and Experimental Neuropsychology·Richard J SiegertDavid Abernethy
Jul 13, 2005·Archives of Neurology·M Leann DoddJ Eric Ahlskog
Oct 18, 2005·Neuropsychologia·Ellen Seiss, Peter Praamstra
Dec 11, 2007·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Sofie MoresiJelle Jolles

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Citations

Aug 28, 2021·Brain Imaging and Behavior·Rea Rodriguez-RaeckeMatthias Wittfoth

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