PMID: 6106099Aug 30, 1980Paper

Response to pneumococcal polysaccharide vaccine in patients with untreated Hodgkin's disease. Children's Cancer Study Group Report

Lancet
J AddiegoD Hammond

Abstract

Patients with Hodgkin's disease (HD) have a high risk of overwhelming pneumococcal infections after splenectomy. Previous studies have shown that HD patients given polyvalent pneumococcal polysaccharide (PPS) vaccine after immunosuppressive therapy have a suboptimum antibody response. This study shows significant antibody response in HD patients to PPS vaccine given before radiation and chemotherapy. The same response was obtained whether the vaccine was given before or after splenectomy.

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Citations

Nov 1, 1991·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·G A Bruyn, R van Furth
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Dec 7, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lorry G Rubin Infectious Diseases Society of America
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May 1, 1988·Thorax·R T White
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Oct 1, 1989·The British Journal of Surgery·J H Shaw, C G Print
Oct 1, 1985·Kidney International·J NikoskelainenM Leinonen

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