Responses of heat stressed chickens to exogenous reverse triiodothyronine (rT3)

Zentralblatt für Veterinärmedizin. Reihe A
S BobekJ Niezgoda

Abstract

Heat stress is accompanied by a decrease in basal metabolic rate and plasma thyroid hormones. Unlike 3,5,3'-triiodothyronine (T3) and thyroxine (T4), 3,3',5'-triiodothyronine (rT3) displays hypometabolic properties and antagonizes the hypermetabolic effect of T3. This study analyses the role of rT3 in heat (38-39 degrees C) stressed immature chickens. Two experiments which differed in frequency of rT3 injections (one or two times a day), duration of heat stress (72 or 48 h) and blood sampling were performed. The dose was 14 micrograms rT3/100 gb.wt./injection (s.c.). It has been shown that rT3 treatment aggravates heat stress symptoms (enhances circulating corticosterone, catecholamines and free fatty acids) and increases mortality. The critical survival time of the rT3 treated and heated birds was at first 24 h of stress. No more chickens died during the next days of the experiment despite the continuation of rT3 injection, suggesting that rT3 might disturb the adaptation to heat. Reverse T3 in heat stressed chickens led to the highest reduction in food consumption (69.9%) and body weight gain (14.0% compared to initial weight). The opposite effect in water consumption (216.9%) was observed. In a neutral environment, rT3 signi...Continue Reading

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Citations

Nov 5, 2005·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·J NiezgodaD Wrońska-Fortuna
May 22, 2002·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·S BobekT Jacek

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