Responses of the aquatic midge Chironomus riparius to DEET exposure

Aquatic Toxicology
Diana CamposJoão L T Pestana

Abstract

N,N-diethyl-3-methylbenzamide (DEET) is the active ingredient of many commercial insect repellents. Despite being detected worldwide in effluents, surface water and groundwater, there is still limited information on DEET's toxicity toward non-target aquatic invertebrates. Thus, our main objective was to assess the effects of DEET in the life cycle of Chironomus riparius and assess its biochemical effects. Laboratory assays showed that DEET reduced developmental rates (reduced larval growth, delayed emergence) of C. riparius larvae and also caused a decrease in the size of adult midges. Concerning the biochemical responses, a short exposure to DEET caused no effects in lipid peroxidation, despite the significant inhibition of catalase and glutathione-S-transferase activities and of total glutathione contents. Moreover, inhibition of acetylcholinesterase activity was also observed showing neurotoxic effects. Environmental risk assessment of insect repellents is needed. Our results showed moderate toxicity of DEET toward C. riparius, however, due to their mode of action, indirect ecological effects of DEET and of other insect repellents cannot be excluded and should be evaluated.

References

Jun 1, 1979·Analytical Biochemistry·H OhkawaK Yagi
Dec 1, 1996·Bulletin of Environmental Contamination and Toxicology·L GuilherminoA M Soares
Feb 27, 1999·Toxicological Sciences : an Official Journal of the Society of Toxicology·G P SchoenigE I Goldenthal
Apr 9, 1999·Medical and Veterinary Entomology·E B DoganP A Rossignol
Jul 1, 1961·Biochemical Pharmacology·G L ELLMANR M FEATHER-STONE
Mar 8, 2005·Archives of Environmental Contamination and Toxicology·J SeoH-G Hur
Mar 15, 2008·Science·Mathias DitzenLeslie B Vosshall
Apr 23, 2008·Proceedings of the National Academy of Sciences of the United States of America·Yuanfeng XiaLaurence J Zwiebel
Jun 25, 2008·Environmental Science and Pollution Research International·Ursula Klaschka
Aug 20, 2008·Proceedings of the National Academy of Sciences of the United States of America·Zainulabeuddin Syed, Walter S Leal
May 5, 2010·Proceedings of the National Academy of Sciences of the United States of America·Nina M StanczykLinda M Field
Aug 28, 2010·Neuron·Youngseok LeeCraig Montell
Jun 29, 2011·The Science of the Total Environment·P CalzaC Minero
Aug 26, 2011·Journal of Insect Science·José G Crespo
Sep 14, 2011·Integrated Environmental Assessment and Management·Dallas AronsonPhilip H Howard
Oct 19, 2011·Integrated Environmental Assessment and Management·J A WeeksA I Nikiforov
Jan 3, 2012·The Science of the Total Environment·Marianne StuartAlwyn Hart
Jan 25, 2012·Neuropharmacology·Jonathan D Bohbot, Joseph C Dickens
Oct 29, 2014·Proceedings of the National Academy of Sciences of the United States of America·Pingxi XuWalter S Leal
Dec 20, 2014·The Science of the Total Environment·Andreia C M RodriguesJoão L T Pestana
Dec 23, 2014·Current Opinion in Insect Science·Walter S Leal
Sep 29, 2015·Environmental Pollution·Andreia C M RodriguesJoão L T Pestana

❮ Previous
Next ❯

Citations

Dec 16, 2016·Ecotoxicology and Environmental Safety·Althiéris S SaraivaAmadeu M V M Soares
Jan 27, 2018·Ecotoxicology·Frederico Guilherme de Souza BeghelliViviane Moschini Carlos
Oct 9, 2019·Pest Management Science·Aline Silvestre Pereira DornelasJoão L T Pestana
Sep 13, 2019·The Science of the Total Environment·Ana-Belén Muñiz-González, José-Luis Martínez-Guitarte
Nov 24, 2018·The Science of the Total Environment·Paul M BradleyIan R Waite
Feb 21, 2021·Environmental Science and Pollution Research International·Ana-Belén Muñiz-GonzálezJosé-Luis Martínez-Guitarte
Feb 12, 2020·The Science of the Total Environment·Gisele Dos Santos MoraisMário Antônio Navarro da Silva

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.