Responses of the bovine infundibulum to noradrenaline during the oestrous cycle

Journal of Reproduction and Fertility
R FriedmanF Stormshak


An experiment was conducted to investigate the responses of the bovine infundibulum to noradrenaline in vitro. Twelve beef heifers were killed and examined in equal numbers during pro-oestrus and dioestrus (day 12 of the oestrous cycle). A jugular blood sample was collected from each heifer immediately before killing, and the sera were subsequently analysed by radioimmunoassay for progesterone and oestradiol. A strip of each infundibulum (ipsilateral and contralateral to the ovary bearing the largest follicle or functional corpus luteum) was placed into a tissue bath and sequentially exposed to increasing concentrations of noradrenaline (0.4, 0.8 and 1.6 micrograms ml-1). Changes in frequency and amplitude of isometric contractions and tissue tone were recorded. Infundibula ipsilateral to ovaries bearing the largest follicle in pro-oestrous heifers responded to all concentrations of noradrenaline with greater frequency of contractions than did either contralateral infundibula or both ipsilateral and contralateral infundibula of dioestrous animals (stage of cycle x tissue location interaction, P < 0.01). Changes in the amplitude of contractions induced by noradrenaline did not differ between stages of the cycle studied or the lo...Continue Reading


Aug 1, 1997·Animal Reproduction Science·M Kafi, M R McGowan
Feb 28, 2003·Biology of Reproduction·Jérôme Lapointe, Jean-François Bilodeau

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