Responses to dietary macronutrient distribution of overweight rats under restricted feeding

Annals of Nutrition & Metabolism
Edurne SimónAntonio S Del Barrio

Abstract

Changes in protein and amino acid balance after energy-restricted feeding have scarcely been studied, although it has been suggested that protein utilization may depend on the macronutrient composition of the restricted diet. The aim of this study is to investigate the influence of dietary fat quality and content, during an energy-restricted regime, on body composition and protein metabolism. Therefore, diet-induced overweight rats were divided into three dietary groups: one group was fed on a control diet ad libitum (control) and the other two groups were fed energy-restricted diets (about 60% of control group), which provided a standard amount (20%) of fat (SFR), based on olive oil, or a high amount (60%) of saturated fat (HFR), based on coconut oil. Measurements of body weight, body composition, serum biochemical parameters and the assessment of the hepatic and muscular protein response were performed. Similar results were found comparing weight losses and serum parameters in both deprived groups, although the high-fat-restricted rats (HFR group) showed a greater reduction in the subcutaneous fat depot and of total body fat. After both energy-restricted treatments, the serum amino acid concentration was reduced while the uri...Continue Reading

Citations

Jun 17, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Paul S MacleanMatthew R Jackman
Nov 18, 2018·Frontiers of Medicine·Xiaojiao ZhengWei Jia

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