Resting Motor Threshold, MEP and TEP Variability During Daytime

Brain Topography
Esther M Ter BraackMichel J A M van Putten

Abstract

Humans show a variation in physiological processes during the day. To reliably assess (changes in) cortical excitability with transcranial magnetic stimulation (TMS), it is relevant to know the natural variation in TMS readouts during the day. In case of significant daytime variations, this should be taken into account when scheduling (follow-up) measurements. This study aims to evaluate the influence of the time of day on the resting motor threshold (RMT), motor evoked potential (MEP) and TMS evoked potential (TEP) in healthy controls. TMS-EMG-EEG was recorded in 16 healthy subjects. At both motor cortices, we administered 75 pulses at an intensity of 110% RMT. Subjects were stimulated during five sessions in one day (8:00 AM, 10:30 AM, 1:00 PM, 3:30 PM and 6:00 PM) while keeping the stimulation intensity constant. We compared the TEP waveforms between the five sessions with a cluster-based permutation analysis, and the RMT and MEP amplitude with rmANOVA. In general there were no significant differences between the five sessions in the RMT, MEP amplitude or TEP. Only for the left side, N100 amplitude was larger at 3:30 PM than 10:30 AM. The standard deviation of the P30 and N100 amplitude was significantly higher between subje...Continue Reading

References

May 11, 1985·Lancet·A T BarkerI L Freeston
Nov 1, 1993·The Journal of Physiology·T KujiraiC D Marsden
May 12, 1998·The Journal of Physiology·R HanajimaI Kanazawa
Feb 12, 2002·Journal of Biological Rhythms·Jeanne F Duffy, Derk-Jan Dijk
Jan 31, 2004·Epilepsy & Behavior : E&B·Milena K PavlovaEdward B Bromfield
Jul 27, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Lisa KoskiJohn M Stern
Feb 21, 2006·Experimental Brain Research·Michelle N McDonnellUlf Ziemann
Mar 10, 2006·Experimental Brain Research·V K KimiskidisK R Mills
Jun 27, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C BonatoP M Rossini
Apr 3, 2007·Journal of Neuroscience Methods·Fabio MorbidiSimone Rossi
May 23, 2007·Journal of Neuroscience Methods·Eric Maris, Robert Oostenveld
Dec 8, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Robert ChenUlf Ziemann
Mar 5, 2008·Current Opinion in Neurology·Jerome Engel
Jun 10, 2008·Human Brain Mapping·Pantelis LioumisSeppo Kähkönen
Feb 26, 2009·Brain Topography·Carlo Miniussi, Gregor Thut
Apr 29, 2009·Sleep Medicine Reviews·Wytske Aelig Hofstra, Al Wytze de Weerd
Jul 22, 2009·Neurology·R A B BadawyS F Berkovic
Oct 17, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Simone RossiUNKNOWN Safety of TMS Consensus Group
Dec 17, 2009·Brain Topography·Risto J Ilmoniemi, Dubravko Kicić
Jan 13, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sebastian H Doeltgen, Michael C Ridding
Aug 5, 2010·NeuroImage·Florinda FerreriPaolo Maria Rossini
Nov 26, 2010·NeuroImage·Hanna Mäki, Risto J Ilmoniemi
Feb 19, 2011·Medical & Biological Engineering & Computing·Reeta J KorhonenJukka Sarvas
Feb 26, 2011·Cerebral Cortex·Nicolas LangWalter Paulus
Feb 9, 2012·Cerebral Cortex·Reto HuberMarcello Massimini
Apr 28, 2012·Seizure : the Journal of the British Epilepsy Association·Alexander MirzoevMary Desrocher
Jun 13, 2012·Journal of Neuroscience Methods·Julio C Hernandez-PavonJukka Sarvas
Aug 11, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Ivana Stetkarova, Markus Kofler
Jan 30, 2013·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Esther M ter BraackMichel J A M van Putten
Sep 3, 2013·Brain Topography·Esther M Ter BraackMichel J A M van Putten
Apr 18, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Isabella PremoliUlf Ziemann
May 20, 2015·Epilepsy & Behavior : E&B·Jolien S van CampenKees P J Braun

❮ Previous
Next ❯

Methods Mentioned

BETA
PCA

Software Mentioned

Matlab
JME

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Esther M Ter BraackMichel J A M van Putten
Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Eric M Wassermann
Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Seppo KähkönenRisto J Ilmoniemi
© 2022 Meta ULC. All rights reserved