Resting-state functional brain connectivity in a predominantly African-American sample of older adults: exploring links among personality traits, cognitive performance, and the default mode network

Personality Neuroscience
Nicole T CraneJessica S Damoiseaux

Abstract

The personality traits of neuroticism, openness, and conscientiousness are relevant factors for cognitive aging outcomes. The present study examined how these traits were associated with cognitive abilities and corresponding resting-state functional connectivity (RSFC) of the default mode network (DMN) in an older and predominantly minority sample. A sample of 58 cognitively unimpaired, largely African-American, older adults (M age = 68.28 ± 8.33) completed a standard RSFC magnetic resonance imaging sequence, a Big Five measure of personality, and delayed memory, Stroop, and verbal fluency tasks. Personality trait associations of within-network connectivity of the posterior cingulate cortex (PCC), a hub of the DMN, were examined using a seed-based approach. Trait scores were regressed on cognitive performance (delayed memory for neuroticism, Stroop for conscientiousness, and verbal fluency for openness). Greater openness predicted greater verbal fluency and greater RSFC between the PCC and eight clusters, including the medial prefrontal cortex, left middle frontal gyrus, and precuneus. Greater PCC-precuneus connectivity predicted greater verbal fluency. Neuroticism and conscientiousness did not significantly predict either cogn...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Aug 23, 2001·Medical Image Analysis·M Jenkinson, S Smith
Nov 15, 2001·NeuroImage·M W WoolrichS M Smith
Oct 23, 2002·Human Brain Mapping·Stephen M Smith
Dec 31, 2002·Proceedings of the National Academy of Sciences of the United States of America·Michael D GreiciusVinod Menon
Jun 15, 2005·Human Brain Mapping·Serge A R B RomboutsPhilip Scheltens
Jun 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·Michael D FoxMarcus E Raichle
Sep 2, 2006·Proceedings of the National Academy of Sciences of the United States of America·J S DamoiseauxC F Beckmann
Jan 19, 2007·NeuroImage·Christopher I WrightDanielle Williams
May 4, 2007·Neuropsychology Review·Christina E Wierenga, Mark W Bondi
Oct 3, 2007·Archives of General Psychiatry·Robert S WilsonDavid A Bennett
Dec 7, 2007·Neuron·Jessica R Andrews-HannaRandy L Buckner
Dec 8, 2007·Cerebral Cortex·J S DamoiseauxS A R B Rombouts
Aug 5, 2008·Neurobiology of Aging·Fabio SambataroVenkata S Mattay
Jul 1, 2003·Journal of Health Psychology·Ryan E RhodesLee W Jones
Feb 20, 2009·International Journal of Geriatric Psychiatry·Brian J AyotteHayden B Bosworth
Oct 9, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Trey HeddenRandy L Buckner
Dec 29, 2009·Neurobiology of Aging·Jonathan JacksonDenise Head
Jul 20, 2010·Journal of Neurology, Neurosurgery, and Psychiatry·T GiliM Bozzali
Feb 5, 2011·Neuroscience Letters·Yoshihiko KunisatoShigeto Yamawaki
Jun 29, 2011·Psychology and Aging·Angelina R SutinAlan B Zonderman
Aug 16, 2011·Neurobiology of Aging·Jessica S DamoiseauxMichael D Greicius
Aug 25, 2011·Neurobiology of Aging·Maja A A BinnewijzendFrederik Barkhof
Oct 8, 2011·NeuroImage·Mark JenkinsonStephen M Smith
Dec 6, 2011·PloS One·Jonathan S AdelsteinMichael P Milham
Jun 28, 2012·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Benjamin ChapmanUNKNOWN Gingko Evaluation of Memory Study Investigators
May 28, 2013·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Antonio TerraccianoSusan M Resnick
Jul 25, 2013·Brain Structure & Function·Adriana SampaioÓscar F Gonçalves
Oct 24, 2013·Proceedings of the National Academy of Sciences of the United States of America·Emily B FalkJohn Schulenberg
Dec 20, 2013·Cognitive, Affective & Behavioral Neuroscience·Moji AghajaniNic J van der Wee
Feb 18, 2014·NeuroImage·Anderson M WinklerThomas E Nichols
May 14, 2014·Personality and Individual Differences·Eileen K Graham, Margie E Lachman
Jan 15, 2015·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Martina LuchettiAngelina R Sutin
Mar 17, 2015·NeuroImage·Raimon H R PruimChristian F Beckmann
Nov 21, 2015·Brain : a Journal of Neurology·David T JonesUNKNOWN Alzheimer’s Disease Neuroimaging Initiative
Jan 27, 2018·Social Cognitive and Affective Neuroscience·Wei-Ting HsuMarvin M Chun

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