Restless legs syndrome, a predictor of subcortical stroke: a prospective study in 346 stroke patients

Sleep Medicine
Anupama GuptaMadhuri Behari

Abstract

The objective of this study was to assess the prevalence of restless legs syndrome (RLS) among patients with stroke and to examine the anatomical correlation between location of stroke and RLS symptoms. We administered a pre-structured sleep questionnaire to consecutive stroke patients seen in our neurology services department over a 3-year period. Unconscious (Glasgow Coma Scale score <15) or aphasic, renally impaired, or neuropathic patients were excluded. Diagnosis of RLS was established according to the criteria of the International Restless Legs Syndrome Study Group (IRLSSG), and polysomnography was conducted. Of 346 stroke patients, 35 (10.11%) fulfilled IRLSSG diagnostic criteria for RLS, which had existed for an average (±standard deviation) of 60 ± 40 months before stroke. The mean age of onset was 52.94 (±10.32) years. Twenty-four patients (68%) had RLS symptoms contralateral to the hemisphere involved in the stroke (eight with unilateral and 16 with grossly asymmetrical RLS). Twenty-nine of 35 patients (82.86%) had imaging evidence of subcortical (16 with hemorrhagic and 13 with ischemic) stroke. Patients with pre-stroke RLS differed from those without it only by subcortical location of the stroke (82.9% vs 31.5% res...Continue Reading

References

Jan 1, 1997·Movement Disorders : Official Journal of the Movement Disorder Society·J MontplaisirP Lespérance
Jan 14, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·W G OndoW D Le
Nov 26, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Joong-Seok KimKwang-Soo Lee
Jan 28, 2004·Archives of Internal Medicine·Klaus BergerChristof Kessler
Oct 7, 2004·Parkinsonism & Related Disorders·Suk Y KangJin-Soo Kim
Dec 20, 2005·Journal of Epidemiology and Community Health·Peter ElwoodJohn Gallacher
Sep 23, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Alexander Unrath, Jan Kassubek
Apr 20, 2007·Parkinsonism & Related Disorders·GianPietro SechiKai Stephan Paulus
Sep 26, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Seung-Jae LeeKwang-Soo Lee
Jun 10, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C A M MedeirosV M S de Bruin
Jan 5, 2013·Sleep·Christopher J EarleyRichard P Allen

❮ Previous
Next ❯

Citations

Jun 1, 2016·Journal of Movement Disorders·Seong-Min Choi
May 10, 2017·QJM : Monthly Journal of the Association of Physicians·C-H ChouJ-T Lee
Oct 27, 2017·Rinshō shinkeigaku = Clinical neurology·Takeo MatsubaraKoichi Hirata
Nov 19, 2018·Acta Neurologica Scandinavica·Tomohiko ShiinaKoichi Hirata
Apr 22, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C L A BassettiV Papavasileiou
Apr 23, 2020·The European Respiratory Journal·Claudio L A BassettiVasileios Papavasileiou
Apr 6, 2021·Aging and Disease·Hongxia CaiGuo-Yuan Yang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine
Al de WeerdRosalia Silvestri
© 2021 Meta ULC. All rights reserved